Justifications for taurine application in case of diabetes mellitus and its complications (Russian clinical experience)
AbstractDiabetes mellitus (DM) according to its prevalence and complications becomes rampant. Constantly appear or improved methods of treatment of patients – medicines and methods of control of blood glucose. The biological function of taurine, opened in the beginning of the XIX century, has long been unclear. The second half of the last century was marked by rapid flowering of interest to Taurin as the main osmoregulatore possessing antioxidant and angioprotection properties during ischemia, radiation defeat and some other pathologies, associated with oxidative stress. Plasma and tissue levels of taurine may vary under different physiological conditions. Concentration of taurine in plasma and platelets in patients with DM type 2 was reduced by almost 1,5 times in comparison with healthy people. Taurine can be used in disorders of carbohydrate metabolism, insulin resistance, metabolic syndrome and diabetes as 2 and type 2, and in cases of complications.
Keywords:diabetes mellitus, taurine, decompensation, glucose, HbA1c, insulin resistance
Endocrinology: News, Opinions, Training. 2013; (3): 39–45.