Role and place of fenofibrate in complex multifactorial therapy of diabetic peripheral neuropathy in patients with type 2 diabetes mellitus

• Alexander S. Ametov
• M.A. Lysenko

AbstractDiabetic peripheral neuropathy (DPN) is one of the most common chronic complications of diabetes mellitus leading to deterioration of the patients’quality of life. Effective methods for the treatment of DPN and improvement of both quality of life and long-term prognosis of the disease remain to be developed. To review pathogenetic mechanisms of DPN, the known methods of DPN treatment and the influence of activation of PPAR-alpha receptors on pathogenesis and outcome of DPN.

Keywords:diabetes mellitus, diabetic neuropathy, fenofibrate

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