Effects of suppressive thyroid therapy on cardiovascular system after surgery for patients with papillary thyroid cancer

• Drozdova I.N.

Abstract

Subclinical thyroid disease is a common clinical problem. Subclinical thyroid disease is defined as serum free T4 and free T3 levels within their respective reference ranges in the presence of abnormal serum TSH levels. Subclinical hyperthyroidism occurs when the serum TSH is below the lower limit of the reference range and the free T4 and T3 concentrations are normal. The most common cause of subclinical hyperthyroidism is exogenous subclinical hyperthyroidism due to unintentional excessive replacement therapy in hypothyroid patients or to intentional TSH suppressive therapy for benign or malignant thyroid disease. However, the clinical significance of subclinical thyroid dysfunction is much debated. Subclinical hyperthyroidism can have repercussions on the cardiovascular system. Patients with subclinical disease have a higher mean 24-h heart rate than do controls in a euthyroid state and have an increased frequency of premature atrial and ventricular beats, left ventricular mass.

Keywords:subclinical hyperthyroidism, suppressive therapy, cardiovascular system, frequency of premature atrial and ventricular beats, left ventricular mass

All articles in our journal are distributed under the Creative Commons Attribution 4.0 International License (CC BY 4.0 license)