ABCD rules and vildagliptin: current approaches in type 2 diabetes management

• Mikhail B. Antsiferov
• M.V. Shestakova

Abstract

Type 2 Diabetes (T2DM) is a progressive disease characterized by deterioration of glycaemia and escalating therapeutic complexity. Recent intervention trials have underscored problems surrounding the risk-benefit balance of most therapeutic strategies in T2DM given, especially the limited cardiovascular advantage of tight glycemic control when set against the co-incident risk of severe hypoglycemia and weight gain. Consequently, therapy should be tailored to the individual. As a result of that process, all current International and Russian Guidelines as well propose an “ABCD” approaches management in type 2 diabetes to determine appropriate glycemic targets based on Age, Body weight, Complications and Disease Duration. ‘ABCD’ aims to guide clinicians in the use of therapeutic agents more effectively, efficiently and safely. Based on these parameters, physicians can select the therapeutic strategy with minimum risk and maximum benefit for each individual.

Keywords:type 2 diabetes mellitus, recommendations, individualized approach, vildagliptin

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