Glucose homeostasis in a healthy person under different conditions. The modern view

• Alexander S. Ametov
• Yaroslava V. Pugovkina
• Natalya A. Chernikova

Abstract

Aim: to evaluate the glucose excursion in healthy volunteers under different conditions using continuous glucose monitoring (blinded mode).

Materials and methods. There were 15 healthy volunteers taken part in investigation. The registration of glucose excursion under standard glucose load (75 g of glucose), fasting, and physical load, walking activities, stair climbing test, cardiac stress test was done under 4-days of continuous glucose monitoring.

Results: in healthy volunteers under the glucose load, fasting, standard physical load the blood values were in target range. Estimated average glucose 5.09±0.38 mmol/l (minimum blood glucose 3.66±0.32 mmol/l, the maximum level glucose 7.15±0.95 mmol/l). Standard deviation wasn't more than 1.

Keywords:glucose homeostasis, fasting glucose, postprandial glucose, glycemic control, continuous glucose monitoring

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