Results of clinical, morphological and functional changes in patients with diabetic preproliferative retinopathy and primary open-angle glaucoma stage 2 during ranibizumab treatment

• Irina V. Vorobyeva
• E.V. Shcherbakova

Abstract

Aim. Efficiency assessment of anti-VEGF therapy for combined ocular pathology: preproliferative diabetic retinopathy with macular edema and with primary open angle glaucoma stage II.

Matherial and methods. We examined patients suffering from diabetes type 2. ALL patients underwent standard ophthalmological diagnostics and optical coherence tomography of the retina and optic nerve, fluorescein angiography, automated perimetry. Patients had anti-VEGF therapy followed by Laser coagulation of the retina. Clinical, morphological and functional changes have been analyzed in the dynamics.

Results. All patients showed an improvement of visual functions; intraocular pressure in all patients was stable by eye drop instillation; retinal thickness in the central zone and volume of neuroretinal rim were decreased by using optical coherence tomography.

Conclusion. An effective approach to the treatment of patients with severe diabetic retinopathy with diabetic macular edema in combination with primary open-angle glaucoma is in early diagnosis and anti-VEGF therapy followed by laser photocoagulation of the retina.

Financial Disclosure. No author has a financial or property interest in any material or method mentioned.

Keywords:diabetes mellitus, diabetic macular edema, diabetic retinopathy, primary open-angle glaucoma, anti-VEGF therapy, ranibizumab

All articles in our journal are distributed under the Creative Commons Attribution 4.0 International License (CC BY 4.0 license)