Status of the pituitary-gonadal sistem and spermatogenesis in troops, participated in the destruction of chemical weapons

• Yuriy Sh. Khalimov
• V.A. Zaytsev
• S.Yu. Matveev

Abstract

Execution of works related to the destruction of chemical weapons has a negative impact on the pituitary-gonadal sistem and spermatogenesis military personnel directly involved in the work with toxic chemi­cals relevant to the CWC.

Aims and objectives. Rate the degree of influence of factors of work related to the destruction of chemi­cal weapons, the state of the pituitary-gonadal sistem and spermatogenesis in the military, directly involved in the work with toxic chemicals related to chemical weapons, depending on the length of service of work performed.

Material and methods. A total of 135 military personnel, of which 75 people are directly involved in the work on the destruction of chemical weapons group of organophosphorus compounds, which were divided into two groups, having an average length of service of chemical weapons 5.4 years and 9.8 years, respec¬tively. The control group consisted of 60 military personnel, not related to facilities for the storage and de¬struction of chemical weapons. Were determined in the blood plasma content of anterior pituitary hormones and testosterone, semen analysis was performed.

Results. It was found that the impact of factors leads to a relative decrease in rates of anterior pituitary hormones and total testosterone, prolactin elevation, as well as the development of polyspermy, mainly due to impaired sperm mobility in military personnel directly involved in the work on the destruction of chemi¬cal weapons. The increase in part-time work with chemical weapons aggravates changes in spermogramme soldiers, amid continuing hormonal dysfunction.

Conclusions. The combined effects of factors of production of chemically hazardous objects have a nega¬tive impact on the pituitary-gonadal sistem and spermatogenesis troops engaged in work for the destruction of chemical weapons.

Keywords:pituitary-gonadal sistem, spermatogenesis, production factors

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