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2 . 2016

Effectiveness of testosterone replacement therapy in case of type 2 diabetes mellitus and male hypogonadism (metabolic and antioxidant evaluation)

Abstract

The risk of hypogonadism in male patients with diabetes mellitus type 2 (T2DM) exceeds the General population. Meanwhile, the
development in the patient with type 2 diabetes mellitus male hypogonadism, diagnosed by reducing the level of total testosterone
less than 12 nmol/l, contributes to the progression of existing metabolic disorders. Use in the absence of contraindications,
testosterone replacement therapy in T2DM patients and male hypogonadism as a rule, allows to break the vicious metabolic circle –
due to positive metabolic and anti-oxidant properties hormone testosterone.

Keywords:type 2 diabetes mellitus, testosterone deficiency, androgenotherapy, oxidative stress

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CHIEF EDITOR
CHIEF EDITOR
Ametov Alexander S.
Honored Scientist of the Russian Federation, Doctor of Medical Sciences, Professor, Head of Subdepartment of Endocrinology, Head of the UNESCO Network Chair on the subject «Bioethics of diabetes as a global problem» of the Russian Medical Academy of Continuous Professional Education (Moscow)
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