Effect of increase in prolactin levels on the development of hyperplastic processes of the mammary glands and the possibility of their drug correction

A central hypothalamic-pituitary dysfunction of reproductive regulation system is caused by high levels of prolactin in blood serum. 25-30% of menstrual cycle and generative dysfunctions are results of hyperprolactinemia. Higher than normal levels of prolactin cause progressive growth of epithelial cells, increase

the quantity of its own and estrogen receptors in mammary glands; consequently enhancing the risk of development of hyperplastic process as well as fatty infiltration of breast parenchyma.

The article describes starting mechanisms of dis-hormonal benign breast disease (mastopathy) development which is triggered hyperprolactinemia and furthermore shows interrelation to overall female reproductive system. This work also presents and analyzes pros and cons of various medical correction schemes of benign mammary dysplasia.