Testosterone therapy evolution. New preparations - new benefits

• Alexander S. Ametov
• Evgeniya Yu. Pashkova

AbstractIn the review article mechanisms of testosterone production regulation as well as possible reasons for its decrease at different stages of man's life are described in depth. In addition main stages of andrology development as the men's health science as well as evolution of hypogonadism therapy possibilities ideas are given. Modern ideas about allocation of testosterone deficiency development risk groups and this condition diagnostic procedure and therapy scheme are given. Additionally comparative assessment of currently available dosage forms of testosterone medications efficacy and safety is given. Recommendations of leading organizations investigative with male health (EAU, ISSAM, RAE) are represented, such as optimal start-up schemes, therapy continuation, monitoring of treatment efficacy and safety, target dates for the achievement of the therapeutic effect.

Keywords:testosterone, men hypogonadism, aging, metabolic syndrome, obesity, testosterone therapy, testosterone deficiency, late onset hypogonadism, erectile dysfunction, Androgel (Testogel)

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