Effect of sodium-glucose linked transporter 2 inhibitor on effectiveness of type 2 diabetes mellitus management

• Krivosheeva A.A.

Abstract

Objective - to evaluate the effectiveness of management of type 2 diabetes on the background of complex hypoglycemic therapy with the addition of empagliflozin from the group of inhibitors of SGLT 2.

Materials and methods. Patients with type 2 diabetes mellitus (DM2) and obesity underwent general clinical examination, carbohydrate metabolism, the level of C-peptide, conducted monitoring of blood glucose and cardiovascular function.

Results. 20 patients with type 2 diabetes were examined. Patients were divided into 2 groups - the patients of the main group were on the therapy of metformin and empaglyflosin, the comparison group was metformin and glimepiride. After 3 months, the dynamics of the indices in the main group of patients and in comparison with the control group was evaluated.

Conclusions. The appointment of the drug empagliflozin in patients with type 2 diabetes provides an effective and safe glycemic control with a low risk of hypoglycemia. The addition of empagliflozin showed a decrease in the variability of glycemia.

Keywords:diabetes mellitus type 2, empagliflozin, continuous monitoring of blood glucose, variability of glycemia

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