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1 . 2018

Advanced features for diabetes mellitus neurological complications treatment

AbstractIn diabetes mellitus the metabolic and microvascular disorders form a deficit of energy-generating phosphates, which leads to cell pathology. The medicine acetyl-L-carnitine helps to restore cell energy imbalance, improving transport of long-chain fatty acid in mitochondria, where they serve as a substrate for adenosine triphosphate formation. Acetyl-L-carnitine has various effect: reduction of oxidative stress, improvement of endothelium condition, antinociceptive action. Acetyl-L-carnitine is a medicine of choice for a large number of patients, in particular of old age, with type II of diabetes mellitus due to multi-purpose activity and efficiency in neurological pathology which патологии характерной for this group of patients: diabetic polyneuropathy and diabetic encephalopathy, asthenia, a low-grade depression.

Keywords:diabetic neuropathy, encephalopathy, asthenia and depression in patients with diabetes mellitus, disorder of cellular metabolism, treatment, acetyl-L-carnitine

Endocrinology: News, Opinions, Training. 2018; 7 (1): 37-41.
DOI: 10.24411/2304-9529-2018-00003


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CHIEF EDITOR
CHIEF EDITOR
Ametov Alexander S.
Honored Scientist of the Russian Federation, Doctor of Medical Sciences, Professor, Head of Subdepartment of Endocrinology, Head of the UNESCO Network Chair on the subject «Bioethics of diabetes as a global problem» of the Russian Medical Academy of Continuous Professional Education (Moscow)
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