Clinical significance of continuous glucose monitoring in diabetic patients on insulin therapy

• Evgeniya Yu. Pashkova
• Alexander S. Ametov
• Nikolay A. Demidov

AbstractThe article is devoted to modern possibilities of basal insulin promoting physiological control of blood sugar during nighttime and mid-meal intervals. New data concerning interpretation and practical use of continuous glucose monitoring together with main postulates of International Consensus on Use of continuous glucose monitoring convened in February 2017 are discussed. Also the results of three comparative trials of insulin Glargine 300 and insulin Glargine 100 demonstrating a more prolonged and stable profile of action and lower glycemic variability in patients getting insulin Glargine 300 are presented. In conclusion three clinical observations of successful transfer from different basal insulins to Glargine 300 are described. The continuous glucose monitoring showed stable flat glucose profile at nighttime with no hypoglycemic episodes and the overall sense of wellbeing that patients reported. So we can confirm that insulin Glargin 300 can provide optimal glucose level during nighttime and can be considered as optimal basal insulin.

Keywords:diabetes mellitus, continuous glucose monitoring, glucose variability, basal insulin, insulin glargine, glucose control, carbohydrate metabolism

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