Glycemic variability in patients with type 2 diabetes mellitus working on night shifts

• Mayya A. Garieva
• Larisa V. Kondratyeva
• Natalya A. Chernikova

Abstract

The article discusses the variability of glycemia in patients with type 2 diabetes mellitus, working on night shifts. As a model of patients with impaired circadian rhythm, the study included train drivers. Imitation of different working conditions (day-night) was carried out in the simulation «driver's cab». A comparative analysis of the results of Continuous Glucose Monitoring System in patients with type 2 diabetes mellitus, working in day and night shifts.

Keywords:diabetes mellitus, workers of locomotive brigades, HbA1c level, simulation of night shifts, Continuous Glucose Monitoring, model of patients with disturbed circadian rhythm

References

1. Garieva M.A., Ametov A.S., Kondratieva L.V. Influence of night shifts workers of locomotive brigades of railway transport on the development of disorders of carbohydrate metabolism. In: III All-Russian Congress of Endocrinology with International Participation "Innovative Technologies in Endocrinology". Book of Abstracts. Moscow, 2017. URL: https://rae-org. ru/events/iii-vserossiyskiy-endokrinologicheskiy-kongress-s-mezhduna-rodnym-uchastiem-innovacionnye (in Russian)

2. Dhar, G.C. Intensive glycemic control implications of the ACCORD, ADVANCE, and VADT trials for family physicians. Can Fam Physician. 2009; 55: 803-4.

3. Monnier L., Mas E., Ginet C., et al. Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes. JAMA. 2006; 295: 1681-7.

4. Kohnert K.D., Heinke P., Fritzsche G., Vogt L., et al. Evaluation of the mean absolute glucose change as a measure of glycemic variability using continuous glucose monitoring data. Diabetes Technol Ther. 2013; 15: 448-54.

5. Dedov 1.1., Shestakova M.V. (eds). Diabetes mellitus: diagnosis, treatment, profilaxis. Moscow. 2011. P. 115. (in Russian)

6. Ametov A.S. Diabetes mellitus type 2. Problems and solutions. Moscow: GEOTAR-Media, 2012. P. 183-208. (in Russian)

7. Rodbard D., Bailey T., Jovanovic L., Zisser H., et al. Improved quality of glycemic control and reduced glycemic variability with use of continuous glucose monitoring. Diabetes Technol Ther. 2009; 11: 71723.

8. Klimontov V.V., Chaff N.E. glycemic variability in diabetes: a tool for assessing the quality of glycemic control and the risk of complications. Sakharniy diabet [Diabetes Mellitus]. 2014; (2): 76-82. (in Russian)

9. Kaminsky L.S. Statistical processing of laboratory and clinical data. Leningrad: Meditsina, 1964: 251 p. (in Russian)

10. Ermakova E. A. influence of glycemia on heart rate variability In patients with type 2 diabetes mellitus and coronary heart disease: Diss. Moscow, 2017. (in Russian)

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