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2 . 2019

The origins of obesity in adults: the role of antenatal and early postnatal periods

Abstract

The extent of the spread and the rate of increase in the incidence of obesity are in the nature of a noninfectious epidemic. Obesity is closely associated with the development of various diseases, including the cardiovascular, digestive systems, the musculoskeletal system, reproductive disorders, the development of malignant neoplasms, which predetermines an increased interest in this problem. The ineffectiveness of measures aimed at the prevention and treatment of obesity, require a review of the main causes and mechanisms of its formation. This article summarizes the basic modern data on the factors contributing to the development of obesity, acting in the fetal period and in the early postnatal period.

Keywords:prenatal programming, eating behavior, obesity

For citation: Kvitkova L.V., Smakotina S.A., Sotnikova Yu.M. The origins of obesity in adults: the role of antenatal and early postnatal periods. Endokrinologiya: novosti, mneniya, obuchenie [Endocrinology: News, Opinions, Training]. 2019; 8 (2): 67-73. doi: 10.24411/2304-9529-2019-12008. (in Russian)

References

1. Razina A.O., Achkasov E.E., Runenko S.D. Obesity: the modern approach to the problem. Оzhireniye i metabolizm [Obesity and Metabolism]. 2016; 13 (1): 3-8. doi: 10.14341/omet201613-8 (in Russian).

2. WHO. Obesity and overweight. Newsletter. http://www.who.int/ru/ news-room/fact-sheets/detail/obesity-and-overweight

3. Pashentseva A.V., Verbovoy A.F., Sharonova L.A. Insulin resistance in therapeutic clinic. Оzhireniye i metabolizm [Obesity and metabolism]. 2017; 14 (2): 9-17. doi: 10.14341/omet201729-17 (in Russian)

4. Borodkina D.A., Gruzdeva O.V., Kvitkova L.V., Barbarash O.L. Is visceral obesity the cause of obesity paradox? Problemy endokrinologii [Problems of Endocrinology]. 2016; 62 (6): 33-39. doi: 10.14341 / probl2016626433-39 (in Russian)

5. Dedov I.I., Shestakova M.V., Galstyan G.R. The prevalence of type 2 diabetes in the adult population of Russia (NATION study). Sakharniy diabet [Diabetes mellitus]. 2016; 19 (2): 104-12. doi: 10.14341/DM2004116-17 (in Russian)

6. WHO. The top 10 causes of death. Fact sheet N°310. Updated May 2014. http://www.who.int/mediacentre/factsheets/fs310/ru

7. Dedov I.I., Mel’nichenko G.A., Romantsova T.I. The strategy of obesity management: the results of All-Russian observational program "Prima-vera". Ozhireniye i metabolizm [Obesity and Metabolism]. 2016; 13 (1): 36-44. doi: 10.14341 / omet2016136-44 (in Russian)

8. Berezina M.V., Mikhaleva O.G., Bardymova T.P. Obesity: mechanisms of development. Sibirskiy meditsinskiy zhurnal [Siberian Medical Journal]. 2012; 114 (7): 15-8. (in Russian)

9. Romantsova T.I. The epidemic of obesity: obvious and probable causes. Ozhireniye i metabolizm [Obesity and Metabolism]. 2011; 8 (1): 5-19. (in Russian).

10. Voznesenskaya T.G. Eating disorders in obesity and their correction. Ozhireniye i metabolizm [Obesity and metabolism]. 2004; 1 (2): 2-6. (in Russian).

11. Netrebenko O.K., Ukraintsev S.E., Mel’nikova I.Yu. Obesity in children: new prevention concepts and approaches. Literature review. Voprosy sovremennoy pediatrii [Problems of Modern Pediatrics]. 2017; 16 (5): 399405. doi: 10.15690/vsp.v16i5.1804 (in Russian)

12. Shcherbakov V.I., Ryabichenko T.I., Skosyreva G.A., Trunov A.N. Mechanisms of fetal programming of obesity in children. Rossiyskiy vestnik perinatologii i pediatrii [Russian Bulletin of Perinatology and Pediatrics]. 2013; 58 (5): 8-14. (in Russian)

13. Kovalenko T.F. Methylation of the mammalian genome. Moleku-lyarnaya meditsina [Molecular Medicine]. 2010; (6): 7-18. (in Russian)

14. Nagaeva E.V., Shiryaeva T.Yu. "Intrauterine programming" of hormonal and metabolic processes and intrauterine growth retardation syndrome. Problemy endokrinologii [Problems of Endocrinology]. 2010; 56 (6): 32-40. (in Russian)

15. Kokhno N.I. Pregnancy: eat or not eat? Disturbed eating behavior: what is the risk of a pregnant woman and what are the consequences for the child? StatusPraesens. Ginekologiya. Akusherstvo. Besplodniy brak [StatusPraesens. Gynecology. Obstetrics. Barren Marriage]. 2015; 3 (26): 96-105. (in Russian)

16. Tsyv’yan P.B., Kovtun O.P. Intrauterine programming of diseases of children and adults. Uspekhi fiziologicheskikh nauk [Successes of the Physiological Sciences]. 2008; 39 (1): 68-75. (in Russian)

17. Grzhibovskiy A.M., Bigren L.O., Tedder Yu.R. Intrauterine programming of adult diseases. Ekologiya cheloveka [Human Ecology]. 2003; (5): 14-22. (in Russian)

18. Belyayeva L.E., Shebeko V.I., Belyayev S.A. Action of stressors during pregnancy and prenatal programming of human diseases. In: Ma-terialy nauchno-prakticheskoy konferentsii "Fundamental’nyye i prikladnyye problemy stressa" [Proceedings of the Scientific-Practical Conference "Fundamental and Applied Stress Problems"]. Vitebsk, 2010: 173-6. (in Russian)

19. Nazarenko L.G., Sorokolat Yu.V., Yakimchuk N.S. Intrauterine programming is a new vector of understanding obstetric and perinatal pathology. Arkhiv klinicheskoy i eksperimental’noy meditsiny [Archive of Clinical and Experimental Medicine]. 2012; 21 (2): 177-9. (in Russian)

20. Vitebskaya A.V. The influence of perinatal factors on the development of obesity in adulthood. Ozhireniye i metabolizm [Obesity and Metabolism]. 2010; (1): 11-4. (in Russian)

21. Dzgoeva F.Kh. Intrauterine nutrition: fetal programming of metabolic syndrome. Ozhireniye i metabolizm [Obesity and Metabolism]. 2015; 12 (3): 10-7. doi: 10.14341/omet2015310-17 (in Russian)

22. Erman M.V., Pervunina T.M. Blockade of Leningrad and... fetal programming. Detskaya bol’nitsa [Children’s Hospital]. 2014; 2 (56): 7-9. (in Russian)

23. Rapoport, S.I., Loboda A.Yu. On the problem of obesity in internal diseases. Klinicheskaya meditsina [Clinical Medicine]. 2008; 86 (11): 1522. (in Russian)

24. Kronenberg H.M., Melmed S., Polonsky K.S., Larsen P.R. Williams Textbook of endocrinology. Obesity and lipid metabolism disorders. Moscow: Rid Elsevier, 2010: 264 p. (in Russian).

25. Smirnova N.N., Kupriyenko N.B. Fetal programming of pathology in adults. Nefrologiya [Nephrology]. 2012; 16 (2): 111-7. (in Russian)

26. Zakharova I.N., Dmitriyeva Yu.A., Gordeyeva E.A. What does the gustatory preferences development in infants depend on? Voprosy sovremennoy pediatrii [Problems of Modern Pediatrics]. 2012; 11 (6): 69-73. (in Russian)

27. Pyr’yeva E.A., Gmoshinskaya M.V., Shilina N.M., Gurchenkova M.A. Early stages in the formation of eating behavior. Rossiyskiy vestnik perinatologii i pediatrii [Russian Bulletin of Perinatology and Pediatrics]. 2017; 62 (3): 125-9. doi: 10.21508/1027-4065-2017-62-3-125-129. (in Russian)

28. Gardanova Zh.R., Salekhov S.A., Esaulov V.I., et. al. Features of influence of emotional stress during pregnancy on the formation of eating behavior in the child. Issledovaniya i praktika v medicine [Research and Practice in Medicine]. 2016; 3 (1): 24-9. doi: 10.17709/2409-2231-2016-3-1-3. (in Russian)

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CHIEF EDITOR
CHIEF EDITOR
Ametov Alexander S.
Honored Scientist of the Russian Federation, Doctor of Medical Sciences, Professor, Head of Subdepartment of Endocrinology, Head of the UNESCO Network Chair on the subject «Bioethics of diabetes as a global problem» of the Russian Medical Academy of Continuous Professional Education (Moscow)
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