To the content
3 . 2019

The effect of hyperhomocysteinemia on the severity of diabetic neuropathy in patients with type 2 diabetes mellitus

AbstractThis article presents of hyperhomocysteinemia on the severity of diabetic neuropathy in patients with type 2 diabetes mellitus.

Keywords:hyperhomocysteinemia, oxidative stress, type 2 diabetes mellitus, diabetic neuropathy

References

1. Tesfaye S., Boulton A.J., Dickenson A.H. Mechanisms and management of diabetic painful distal symmetrical polyneuropathy. Diabetes Care. 2013; 36: 2456-65.

2. The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of Diabetes on the development and progression of long-term complication in insulin-dependent diabetes mellitus. N Engl J Med. 1993; 329: 977-86.

3. Brownlee M. The pathobiology of diabetic complications: a unifying mechanism. Diabetes. 2005; 54: 1615-25.

4. Wang H., Cui K., Xu K., Xu S. Association between plasma homocysteine and progression of early nephropathy in type 2 diabetic patients. Int J Clin Exp Med. 2015; 8 (7): 11174-80.

5. Li J., Shi M., Zhang H., Yan L., et al. Relation of homocysteine to early nephropathy in patients with type 2 diabetes. Clin Nephrol. 2012; 77 (4): 305-10.

6. Brazionis L., Rowley K., Itsiopoulos C., Harper C.A., O'Dea K. Homocysteine and diabetic retinopathy. Diabetes Care. 2008; 31 (1): 50-6.

7. Rudy A., Kowalska I., Str^czkowski M., Kinalska I. Homocysteine concentrations and vascular complications in patients with type 2 diabetes. Diabetes Metab. 2005; 31 (2): 112-7.

8. Jacobsen D.W. Hyperhomocysteinemia and oxidative stress. Arterioscler Thromb Vasc Biol. 2000; 20: 1182-4.

9. Weiss N., Zhang Y.Y., Heydrick S., Bierl C., Loscalzo J. Overexpression of cellular glutathione peroxidase rescues homocyst(e) ine-induced endothelial dysfunction. Proc Natl Acad Sci USA. 2001; 98 (22): 12503-8.

10. Hoogeveen E.K., Kostense P.J., Jakobs C., et al. Hyperhomocysteinemia increases risk of death, especially in type 2 diabetes: 5-year follow-up of the Hoorn Study. Circulation. 2000; 101: 1506-11.

All articles in our journal are distributed under the Creative Commons Attribution 4.0 International License (CC BY 4.0 license)

CHIEF EDITOR
CHIEF EDITOR
Ametov Alexander S.
Honored Scientist of the Russian Federation, Doctor of Medical Sciences, Professor, Head of Subdepartment of Endocrinology, Head of the UNESCO Network Chair on the subject «Bioethics of diabetes as a global problem» of the Russian Medical Academy of Continuous Professional Education (Moscow)
Вскрытие

Journals of «GEOTAR-Media»