Modern methods of diagnosis of the ophthalmic complications of acromegaly

• Viktoriya A. Vardanyan
• Elena V. Doskina

Abstract

Acromegaly is a rare disorder that can cause chiasmal syndrome. Compression of the optic chiasm due to the growth of pituitary adenoma leads to various visual problems manifesting mainly as bitemporal hemianopsia (loss of lateral vision in both eyes). Acromegaly patients need thorough ophthalmic examination which involves visual field test, dilated fundus examination, extraocular muscles motility and chromatic tests.

Keywords:аcromegaly, chiasmal syndrome, Humphrey field exam, bitemporal hemianopsia, pituitary adenoma

References

1. Bolanowski M., Ruchafa M., Zgliczynski W., Kos-Kudfa B., Hubalewska-Dydejczyk A., Lewinski A. Diagnostics and treatment of acromegaly - updated recommendations of the Polish Society of Endocrinology. Endokrynol Pol. 2019; 70 (1): 2-18. DOI: 10.5603/ EP.a2018.0093

2. Egorova E.S. the development of the chiasm syndrome in a pituitary adenoma with suprasellar distribution. Features of the case. Vestnik VGMU [Bulletin of VSMU]. 2018; 17 (5): 52-7. (in Russian)

3. Astorga-Carballo A., Serna-Ojeda J.C., Camargo-Suarez M.F. Chiasmal syndrome: Clinical characteristics in patients attending an ophthalmological center. Saudi J Ophthalmol. 2017; 31 (4): 229-33. DOI: 10.1016/j.sjopt.2017.08.0044. Kan E., Kan E.K., Atmaca A., Atmaca H., Colak R. Visual field defects in 23 acromegalic patients. Int Ophthalmol. 2013; 33 (5): 521-5. DOI: 10.1007/s10792-013-9733-7

5. FOchtbauer L., Olsson D.S., Coopmans E.C., Bengtsson B.A., Norrman L.L., Neggers S.J.C.M., et al. Increased number of retinal vessels in acromegaly. Eur J Endocrinol. 2020; 182 (3): 293-302. DOI: 10.1530/EJE-19-0778

6. Zhang X., Ma J., Wang Y., Li L., Gao L., Guo X., et al. Elevated serum IGF-1 level enhances retinal and choroidal thickness in untreated acromegaly patients. Endocrine. 2018; 59 (3): 634-42. DOI: 10.1007/s12020-017-1511-2

7. Heireman S., Delaey C., Claerhout I., Decock C.E. Restrictive extraocular myopathy: a presenting feature of acromegaly. Indian J Ophthalmol. 2011; 59 (6): 517-9. DOI: 10.4103/0301-4738.86330

All articles in our journal are distributed under the Creative Commons Attribution 4.0 International License (CC BY 4.0 license)