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3 . 2020

Metabolic adverse effects of immunosuppressive drugs after solid organ transplantation: current stage of known problem

Abstract

Understanding of hyperglycemia development mechanisms on current immunosuppressive treatment is necessary to choose the desirable antidiabetic therapy.

Keywords:immunosuppressive therapy, diabetes mellitus after transplantation

Финансирование. Исследование не имело спонсорской поддержки.

Конфликт интересов. Авторы заявляют об отсутствии конфликта интересов.

Для цитирования: Митченко Ю.И., Аметов А.С., Пашкова Е.Ю. Влияние иммуносупрессивной терапии на углеводный обмен у пациентов после трансплантации внутренних органов: современный этап известной проблемы // Эндокринология: новости, мнения, обучение. 2020. Т. 9, № 3. C. 74–76. DOI: https://doi.org/10.33029/2304-9529-2020-9-3-74-76

References

1. Jenssen T., Hartmann А. Post-transplant diabetes mellitus in patients with solid organ transplants. Nat Rev Endocrinol. 2019; 15 (3): 172-88.

2. Pham P.T., Sidhu H.S., Pham P.M., et al. Diabetes mellitus after solid organ transplantation. Edited by K.R. Feingold, B. Anawalt, A. Boyce et al. Endotext [Internet]. 2019. URL: https://www.endotext.org/

3. Dong M., Parsaik A.K., Eberhardt N.L., et al. Cellular and physiological mechanisms of new-onset diabetes mellitus after solid organ transplantation. Diabet Med. 2012; 29 (7): 1-12.

4. Sklyanik I.A., Shamkhalova M. Sh., Shestakova M.V. Posttransplantation diabetes mellitus. Literature review. Sakharniy diabet [Diabetes Mellitus]. 2015; (2): 20-31. (in Russian)

5. Dai C., Walker J.T., Shostak A., et al. Tacrolimus- and sirolimus-induced human в cell dysfunction is reversible and preventable. JCI Insight. 2020; 5 (1): e130770.

6. Zinman B., Wanner C., Lachin J.M., et al. Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. N Engl J Med. 2015; 373: 2117-28.

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CHIEF EDITOR
CHIEF EDITOR
Ametov Alexander S.
Honored Scientist of the Russian Federation, Doctor of Medical Sciences, Professor, Head of Subdepartment of Endocrinology, Head of the UNESCO Network Chair on the subject «Bioethics of diabetes as a global problem» of the Russian Medical Academy of Continuous Professional Education (Moscow)
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