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4 . 2020

Effects of the combination metformin and iSGLT-2 in clinical use

Abstract

The research is devoted to the study of the effects of a combination of drugs metformin and iSGLT-2 on the treatment of type 2 diabetes. Initial combination treatment with an iSGLT2 inhibitor and metformin shows high efficacy, results in a clinically meaningful and statistically significant improvement in glycemic control and weight loss.

Keywords: diabetes, iSGLT-2, chronic kidney disease, glycated hemoglobin, body mass index Funding.

Funding. The study had no sponsor support.

Conflict of interests. The authors declare no conflict of interests.

For citation: Makarshina D.A., Zhuravel V.V., Demidova T.Yu., Titova V.V. Effects of the combination metformin and iSGLT-2 in clinical use. Endokrinologiya: novosti, mneniya, obuchenie [Endocrinology: News, Opinions, Training]. 2020; 9 (4): 97–8. DOI: https://doi.org/10.33029/2304-9529-2020-9-4-97-98 (in Russian)

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CHIEF EDITOR
CHIEF EDITOR
Ametov Alexander S.
Honored Scientist of the Russian Federation, Doctor of Medical Sciences, Professor, Head of Subdepartment of Endocrinology, Head of the UNESCO Network Chair on the subject «Bioethics of diabetes as a global problem» of the Russian Medical Academy of Continuous Professional Education (Moscow)
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