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1 . 2021

Vascular aging and type 2 diabetes mellitus


Cardiovascular diseases remain the leading cause of morbidity and mortality in developed countries, and chronological age, along with others, is the main risk factor for their development. Current strategies for increasing life expectancy and improving health require physicians to understand the inter-individual differences in age-related functional changes known as early vascular aging. The aim of this review article is to summarize the current data on the prognostic role of increased arterial stiffness in the verification of early vascular aging in people with type 2 diabetes-associated cardiovascular diseases and to identify individuals for the earliest prevention of cardiovascular diseases. During the discussion, modern approaches to managing vascular age and correcting risk factors for early vascular aging, such as physical activity, a low-calorie diet, and limiting sodium intake, are considered. Emphasis is placed on the effectiveness of the prevention of vascular aging with various hypoglycemic drugs.

Keywords:vascular aging, type 2 diabetes mellitus, arterial stiffness

Funding. The study had no sponsor support.

Conflict of interests. The authors declare no conflict of interests.

For citation: Rubtsov Yu.E., Kryukov E.V., Khalimov Yu.Sh. Vascular aging and type 2 diabetes mellitus. Endokrinologiya: novosti, mneniya, obuchenie [Endocrinology: News, Opinions, Training]. 2021; 10 (1): 52-61. DOI: (in Russian)


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Ametov Aleksandr Sergeevich
Doctor of Medical Sciences, Professor, Head of Subdepartment of Endocrinology of the Russian Medical Academy of Continuing Professional Education, a member of the Governing Board of the Russian Association of Endocrinologists (Moscow)
Medicine today

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