Relationship between obesity and hypertension: how can the effect on appetite reduce blood pressure?
AbstractOver the past half century, there has been a rapid increase in the number of cases of obesity, due to a significant change in lifestyle. First of all, this can be attributed to the easy availability of high-calorie foods and a decrease in physical activity. So, according to World Health Organization (WHO), the number of overweight and obese people was 2 billion people in 2016, moreover, the problem is relevant among children - overweight was detected in 41 million children under 5 years old and in 340 million people from 5 to 19 years old (WHO Fact sheet, 2017). In addition to the fact that obesity is an aesthetic defect, with increasing weight there is an increase in the frequency of a number of comorbidities, for example, type 2 diabetes mellitus, dyslipidemia, and obstructive sleep apnea syndrome. At the end of the 20th century, it also became clear that overdeveloped adipose tissue was associated with arterial hypertension.
This article discusses the pathogenetic relationship of increased blood pressure and the presence of obesity, and also considers how weight loss affects the change in blood pressure, especially in the framework of drug correction of excess adipose tissue.
Keywords:obesity, overweight, blood pressure, weight loss, sibutramine, insulin resistance
Funding. The study had no sponsor support.
Conflict of interest. The authors declare no conflict of interest.
For citation: Ametov A.S., Pyanykh O.P., Golodnikov I.I. Relationship between obesity and hypertension: how can the effect on appetite reduce blood pressure? Endokrinologiya: novosti, mneniya, obuchenie [Endocrinology: News, Opinions, Training]. 2021; 10 (2): 65-73. DOI: https://doi.org/10.33029/2304-9529-2021-10-2-65-73 (in Russian)
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