Hypothyroidism: a difficult diagnosis

• Yuliya A. Dolgikh
• Tatyana V. Lomonova

Abstract

Primary hypothyroidism is one of the most common endocrine diseases. This is a clinical syndrome that develops as a result of persistent deficiency of thyroid hormones or a decrease of their biological effect at the tissue level. The symptoms of the disease are nonspecific and therefore the first contact doctor can be a variety of specialists. It seems relevant to screen thyroid insufficiency by determining the level of thyroid-stimulating hormone in patients with various pathologies. These include diseases of the cardiovascular system, obesity, disorders of lipid and carbohydrate metabolism, neuropsychiatric disorders, anemia, diseases of the reproductive system.

Keywords:hypothyroidism, arterial hypertension, metabolic syndrome, infertility, cognitive impairment, anemia, diabetes mellitus

References

1. Fes'kova A.A., Drobysheva E.S., Ovsyannikov E.S., Chernov A.V. Clinical features of arterial hypertension at subdinical thyroid hypofunction. Prikladnye informacionnye aspekty mediciny [Applied Information Aspects of Medicine]. 2015; 18 (6): 35-42. (in Russian)

2. Nekrasova T.A., Strongin L.G., Morozova E.P., Durygina E.M., Kazakova L.V. Modifying influence of subdinical hypothyroidism on arterial hypertension: relationship to masked treatment failure, circadian blood pressure profile and target organs status. Klinicheskaya i ehksperimental'naya tireoidologiya [Clinical and Experimental Thyroidology]. 2015; 11 (2): 55-62. (in Russian)

3. Vernigorodsky V.S., Vlasenko M.V., Palamarchuk A.V., Nezhinskaya-Astapenko Z.P., Litvinova S.V., Vilchinskaya N.V., et al. Therapeutic "masks" of hypothyroidism. Miznarodnij endokrinologicnij zurnal [International Journal of Endocrinology]. 2018; 14 (5): 503-7. (in Russian)

4. Nekrasova T.A., Strongin L.G., Ledentsova O.V. Hematological disturbances in subdinical hypothyroidism and their dynamics during substitution therapy. Klinicheskaya meditsina [Clinical Medicine]. 2013; 9: 29-33. (in Russian)

5. Dubinina I.I., Berstneva S.V. Levothyroxine replacement therapy at diabetes mellitus and hypothyroidism. Effektivnaya farmakoterapiya [Effective pharmacotherapy]. 2018; 9: 28-33. (in Russian)

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