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3 . 2022

Characteristics of cytokines in patients with type 2 diabetes mellitus and acute myocardial infarction

Abstract

The paper analyzes the indicators of the inflammatory response in patients with type 2 diabetes mellitus (T2DM) and ST-segment elevation acute myocardial infarction (STEMI). According to the results of the study, it was revealed that in the group of patients with T2DM and STEMI there was a more pronounced increase in interleukin‑1β, tumor necrosis factor-α, high-sensitivity C-reactive protein compared with the control group without diabetes and STEMI.

Keywords:diabetes mellitus; myocardial infarction; inflammation; cytokines

Funding. The study had no sponsor support.

Conflict of interest. The author declares no conflict of interest.

For citation: Tsyretorova S.S. Characteristics of cytokines in patients with type 2 diabetes mellitus and acute myocardial infarction. Endokrinologiya: novosti, mneniya, obuchenie [Endocrinology: News, Opinions, Training]. 2022; 11 (3): 115–7. DOI: https://doi.org/10.33029/2304-9529-2022-11-3-115-117 (in Russian)

References

1. International Diabetes Federation. IDF Diabetes Atlas. 10thed. 2021.

2. Dedov I.I., Shestakova M.V., Mayorov A. Yu., et al. Standards of specialized diabetes care. Edited by Dedov I.I., Shestakova M.V. (10th edition, revised). Moscow: 2021: 232 p. (in Russian)

3. Bertoni A.G., Burke G.L., Owusu J.A., et al. Inflammation and the incidence of type 2 diabetes: the Multi-Ethnic Study of Atherosclerosis (MESA). Diabetes Care. 2010; 33 (4): 804–10.

4. Petelina T.I., Musikhina N.A., Gapom L.I., et al. Lipid profile and markers of vascular inflammation in patients with stable angina in the presence and absence of type 2 diabetes mellitus. Sakharni diabet [Diabetes Mellitus]. 2017; 20 (3): 194–200. (in Russian)

5. Soldatova O.V., Kubyshkin A.V., Ushakov A.V., et al. Proinflammatory cytokines changes in clinical course of acute myocardial infarction. Bûlletenʹ sibirskoj mediciny [Bulletin of Siberian Medicine]. 2017; 16 (1): 92–100. (in Russian)

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CHIEF EDITOR
CHIEF EDITOR
Ametov Alexander S.
Honored Scientist of the Russian Federation, Doctor of Medical Sciences, Professor, Head of Subdepartment of Endocrinology, Head of the UNESCO Network Chair on the subject «Bioethics of diabetes as a global problem» of the Russian Medical Academy of Continuous Professional Education (Moscow)
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