Background. The management of T2DM requires aggressive treatment to achieve glycemic and cardiovascular risk factor goals. Patients with small duration of the disease is preferable to use drugs that have not exhausting, but rather a protective effect on the function of

Intermittent fasting (IF) regimens have gained considerable popularity in recent years, as some people find these diets easier to follow than traditional calorie restriction (CR) approaches. IF involves restricting energy intake on 1–3 d/wk, and eating freely on the

Dipeptidyl peptidase-4 (DPP-4) inhibitors, oral hypoglycemic agents, augment glucose-dependent insulin secretion and suppress glucagon levels through enhancement of the action of endogenous incretin. Treatment with DPP-4 inhibitors is generally well tolerated due to low risk

Modern algorithms ofmedical care indiabetescontaininstructions for useof new groups ofantidiabetic drugs: SGLT2 inhibitors, DPP-4 inhibitors, GLP-1 receptor agonists. Each of these classeshas a unique mechanismof action thatdiffers from the oldoral hypoglycemic

The prevalence of obesity and overweight has grown by an average of 75 percent over the past decade and now is estimated as 1.7 billion people. The combination of metabolic and hemodynamic abnormalities with abdominal obesity type is known as “metabolic syndrome”

Diabetes mellitus (DM) is one of the most urgent health and social problems in modern health care. In recent years, drew the attention of a wide spread of osteoporosis (OP) in patients with DB the majority of the experts called osteoporosis underrated complication of

Primary hypothyroidism is one of the most common endocrine diseases. Primary hypothyroidism prevalence in the general population changes from 3,8 to 4,6%. According to the Whickham survey annual incidence of hypothyroidism in the UK was 4,1 per 1000 women and 0,6 per 1000

The article describes different approaches to the treatment of type 2 diabetes mellitus (T2DM) and their impact on micro- and macrovascular complications. You can appreciate ADVANCE study results and description of gliclazide CF administration advantages in long term

Objective. Recombinant human platelet-derived growth factor (rhPDGF) is used topically in the treatment of diabetic lower-extremity ulcers. There have been few meta-analyses of the efficacy of rhPDGF in this treatment context. The aim of this study was to perform an updated

Nodules of the thyroid is one of the most common diseases in endocrinology. According to some sources, the occurrence of nodules of the thyroid in the population reaches 50%. Malignant tumors of the thyroid gland, though, and have a favorable prognosis, are the most frequent

Subclinical thyroid disease is a common clinical problem. Subclinical thyroid disease is defined as serum free T 4 and free T 3 levels within their respective reference ranges in the presence of abnormal serum TSH levels. Subclinical hyperthyroidism occurs when the serum TSH

Testosterone replacement therapy in patients with type 2 diabetes mellitus, visceral obesity and androgenotherapy improves metabolic characteristics of carbohydrate and lipid metabolism, and elimination of state glucolipotoxicity.

The article describes the characteristics and clinical features of pulmonary lesions in diabetes mellitus. The paper contains an analysis of modern studies, scientific articles devoted to disorders of the respiratory system in patients with diabetes mellitus

The paper analyzes the relationship between markers for smoldering chronic inflammation and oxidative stress with diabetic neuropathy development in patients with type 2 diabetes. Analysis shows that fenofibrate appears to decrease smoldering chronic inflammation intensity,