Topic number
4 . 2015
Type 2 diabetes mellitus
Content
Editorial

Editorial

Abstract
News of endocrinology

Endocrinology news

Abstract
Reviews

Saxagliptin in the treatment of diabetes mellitus type 2: focus on the cardiovascular safety

Abstract
The purpose of this article is to describe the efficiency of selective and competitive inhibitor of dipeptidyl peptidase-4 saxagliptin and saxagliptin/metformin extended-release (XR) fixed-dose combination. This article presents results of the assessment of cardiovascular

Out-patient profile of glucose and new touch technology – the timely help in management of diabetes mellitus

Abstract
Multifactorial approach underlies the bottom of modern management of type 2 diabetes. Currently special attention to glycemic excursion severity is given as the factor that leads to diabetes mellitus prognosis impairment. In the article continuous glucose monitoring systems

Gliclazide MR among sulfonylureas drugs: primus inter pares

Abstract
Sulfonylureas take a central place in the pharmacotherapy of diabetes mellitus type 2 for many years. The main purpose of this article is to highlight the current scientific data about gliclazide. Gliclazide is sulfonylurea drug with unique properties, which distinguish it

Emerging targets for therapeutic development in diabetes and its complications: the RAGE signaling pathway

Abstract
Types 1 and 2 diabetes are on the rise worldwide. Although the treatment of hyperglycemia has benefited from recent advances, aggressive efforts tomaintain euglycemiamay be fraught with risk, especially in older subjects or in subjects vulnerable to hypoglycemic unawareness.

Prandial glucagon-like peptide-1 receptor agonists in clinical practice

Abstract
Metabolic effects glucagon-like peptide-1 receptor agonists (GLP-1 RA) are the result of glucose-stimulated insulin secretion enhancement, inhibition of glucagon secretion, slowing gastric emptying and increased satiety. These properties indicate that GLP-1 RA may be

Diabetes and the plasticity of sensory neurons

Abstract
Diabetes mellitus targets sensory neurons during the development of peripheral neuropathy. While polyneuropathy is often routinely considered as another ‘microvascular’ complication of diabetes mellitus, this concept may no longer address the complexities and
Education

Syndrome of hypothyrosis: lecture

Abstract
The article considers with questions of etiology, pathogenesis, clinic and treatment of the hypothyrosis.
Original research

Optimization of diabetes mellitus type 2 treatment in a disease onset

Abstract
In article results of application of Reduxine®Met (sibutramin+metformine) or metformin at patients with diabetes mellitus type 2 in a disease debut according to endocrinological office of policlinic of Regional clinical hospital No. 3 of Chelyabinsk are analysed.
Announcements

Announcements

Abstract

All articles in our journal are distributed under the Creative Commons Attribution 4.0 International License (CC BY 4.0 license)

CHIEF EDITOR
CHIEF EDITOR
Ametov Alexander S.
Honored Scientist of the Russian Federation, Doctor of Medical Sciences, Professor, Head of Subdepartment of Endocrinology, Head of the UNESCO Network Chair on the subject «Bioethics of diabetes as a global problem» of the Russian Medical Academy of Continuous Professional Education (Moscow)
Вскрытие

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