The review presents data from comparative randomized clinical trials conducted in different countries, with the participation of more than 500 subjects assessing the effectiveness of a low-calorie high-protein diet that include partial meal replacement in individuals with

Diabetes mellitus type 2 (T2DM) is a global problem of world health. Clinical studies show that early glucose-lowering therapy reduces the risk of complications, and recommend the use of lifestyle changes along with the initial combination therapy. Management of T2DM can be

At the moment of verification of a type 2 diabetes mellitus (DM2) diagnosis, more than 50% of patients show clinical signs of atherosclerosis. Meanwhile, there have been no complex researches that seek to enable the estimation of the character and interrelations of the

With diabetes mellitus type 1 (DM1), an absolute insulin deficiency is observed in the body due to the destruction of β -cells. Therefore, life-substituting insulin therapy is, to date, the only method for treating patients with this pathology. The leading role in the

Management of patients with diabetes mellitus and diabetic foot syndrome represents a certain difficulty for the doctor, considering options general and local treatment, the need for long exposure, high economic component, both for the patient and his family, and for health

Aim - to compare the microbiome of chronic diabetic foot ulcers (DFU) without signs of infection using conventional culture techniques and mass - spectrometry approach of microbial markers. Material and methods. The samples from 17 DFU without signs of infection were sent to

To examin the anthropometric and hormonal characteristic of constitutional delay of puberty (CDP) in boys with overweight/obesity. Methods. The study included 89 boys aged 14.5+0.8 years with CDP. The boys with deficiency weight were excluded from the study. The other

The paper is devoted to the analysis of the case of the atypical acute myocardial infarction at the patient with the low cardiovascular risk and without the family history of cardiovascular events. It was shown that the development of the atypical acute myocardial infarction

The peculiarity of the clinical case is the difficulty of diagnosing the syndrome Chiari-Frommel in a patient previously operated on for the uterine fibroids.

The use of integrated approach in the treatment of type 2 diabetes mellitus (DM2) leads to improved glycemic and lipid control, by that reducing glucose and lipotoxicity, reducing oxidative stress, and improving body weight. Antioxidant therapy is pathogenetic in relation to

The structure and clinico-laboratorial characteristics of reproductive disorders in men who received complex therapy for neurogliocytoma were investigated. It was found that after therapy for neurogliocytoma in men, prevalence of reproductive system disorders is extremely

Diabetes mellitus type 2 is a socially significant disease that increases the risk of development of disability and mortality of the able-bodied population. The prevalence of diabetes mellitus is steadily increasing, so that the importance of its prevention becomes more

Clinical and laboratory efficacy of α-lipoic acid (ALA) in type 2 diabetes mellitus (DM2) patients with diabetic polyneuropathy (DPN) was evaluated. There were 59 DM2 patients with DPN under observation: 27 (45.8%) women and 32 (54.2%) men. 30 patients were additionally

Thyrotropinoma is a rare benign pituitary tumor. It appears only in 1-2% cases among all the pituitary hormone producing adenomas. Usually thyrotropinoma produces only one hormone, but sometimes (in 25%) it can produce many. Commonly the first symptoms of the disease are

Objectives - to study the clinical and hormonal characteristics of delayed puberty in girls with hypergonadotropic hypogonadism. Methods. 33 girls, 14.9 ± 0.7 years, with delayed puberty were examined. Entry criteria were the absence of secondary sex characteristics at

Metformin is one of the most widely used antidiabetic drugs in the management of type 2 diabetes. The mechanism of action is well described, there are evidence of cardioprotective, antitumor and antiaging properties of the metformin. Moreover there areexpectations for

This article presents effect of metformin on homocysteine blood level and vascular endothelium function in patients with type 2 diabetes mellitus.

Primary chronic adrenocortical insufficiency is quite rare in the general population - it occurs 40-110 times per 1 million population on annual basis. This clinical case describes the typical development of primary adrenal insufficiency of young male, its treatment with

The work demonstrated a positive antioxidant activity against the background of hormone replacement therapy with testosterone in patients with type 2 diabetes mellitus and androgen deficiency.

Aim. To study clinical and laboratory characteristics of patients with disorders of sex development 46XY, androgen insensitivity syndrome. Subjects and methods. It was included 52 patients and formed group with disorders of sex development (DSD) 46XY, androgen insensitivity

Obesity is one of the main health problems of our time. To identify the causes of the disease, various types of diagnostics are used. The aim of this work is to analyze these methods and based on their merits and demerits, to present a classification developed in 2014 that

We evaluated microcirculation parameters in patients with diabetes mellitus type 2 by digital capillaroscopy depending on the C-peptide secretion level. 1st group included patients with C-peptide <1000 pmol/l and 2nd group was consisted of patients with C