Since obesity is a chronic recurrent disease that requires long-term complex therapy, high requirements for efficacy and safety are imposed on drugs for its treatment. Currently, orlistat is the safest means, because it is not absorbed into the blood and does not have a

Nutrition is one of the main blocks in the foundation of diabetes management, along with weight loss, regular physical activity and drug therapy. Today we have a large variety in the choice of dietary strategies. There are non-significant or marginal differences in weight

Diabetic nephropathy is the main cause of end-stage renal disease. The appearance of diabetic nephropathy is a marker of multisystem failure and has an unfavorable prognostic value. Patients with renal failure have higher morbidity, mortality and risk of hypoglycemia. The

This article is а review of the potential mechanism attributed to sarcopenia in diabetes. Patients with diabetes are characterized with three times higher risk of sarcopenia than subjects without diabetes due to accelerated decline of muscle mass and strength. Numerous

Diabetic foot syndrome is one of the most severe socially significant complications of diabetes mellitus. The most dramatic consequences of this complication include high level of amputations of the lower limbs. Long-term diabetic foot ulcers time of healing is quite a

In this article we have presented a review of studies on antioxidant treatment of diabetes mellitus complications - diabetic polyneuropathy, the frequency of which, according to different authors, varies from 12 to 95%. This pathology can lead to the development of the most

MODY was first described by R. Tattersall and S. Frajans in 1975 as a rare, genetically determined group of diseases characterized by different variants of mutations of the genes responsible for insulin secretion. At the moment, there are 13 known candidate genes and,

The article presents a case of clinical observation of a patient with a rare genetic syndrome. The peculiarity of the clinical case is the difficulty of diagnosis in children at an early age. The article shows the role of studying the history, clinical and laboratory

Diabetes is a fast growing chronic metabolic disorder around the world. Dipeptidyl peptidase-4 (DPP-4) is a new promising target during type 2 diabetes glycemic control. Thus, a number of potent DPP-4 inhibitors were developed and play a rapidly evolving role in the