Editorial
Original research
The effect of hyperhomocysteinemia on the level of antioxidant enzymes in the blood and on the severity of diabetic neuropathy in patients with type 2 diabetes mellitus
Abstract
Aim. To assess the effect of hyperhomocysteinemia on the level of antioxidant enzymes in the blood and on the severity of diabetic neuropathy (DN) in patients with type 2 diabetes. Material and methods . 30 patients with type 2 diabetes and with DN were divided into 2
Glycemic variability in patients with type 2 diabetes mellitus working on night shifts
Abstract
The article discusses the variability of glycemia in patients with type 2 diabetes mellitus, working on night shifts. As a model of patients with impaired circadian rhythm, the study included train drivers. Imitation of different working conditions (day-night) was carried
Reviews
Insulin resistance and lipotoxicity - 2 facets of one problem
Abstract
The review presents an analysis of clinical and experimental data on the pathogenetic mechanisms of insulin resistance and lipotoxicity in diabetes mellitus. The paper presents their interrelation and role in the development of carbohydrate metabolism disorders from the
Structured analysis of the ambulatory glycemic profile in patients with diabetes mellitus
Abstract
Given the inexorably growing number of patients with diabetes mellitus, their adherence to sufficient glycemic control is extremely important. And now an increasing number of patients are beginning to use modern technology to control their disease. This applies, inter alia,
Possibilities of metabolic therapy in the treatment of micro-and macrovascular complications of diabetes mellitus: the role of taurine
Abstract
Authors of the review article analyzed the results of foreign and Russian research works to the study of the role of taurine in the pathogenesis of vascular complications of diabetes mellitus. The metabolic effects of taurine have been described in detail, as well as the
Possibilities of early combination therapy with sitagliptin and metformin in the correction of metabolic disorders in patients with type 2 diabetes mellitus
Abstract
The current task of modern diabetology remains the search for an optimal therapeutic approach that increases the efficiency of treatment in patients with type 2 diabetes. Monotherapy with glucose-lowering drugs does not always lead to the achievement of target values of
Obesity as a non-infectious epidemic of the XXI century. Modern ideas about the pathogenesis, risks and approaches to pharmacotherapy
Abstract
The article considers in detail the mechanisms of obesity development as well as epidemiological and pathogenetic aspects of the link between obesity and metabolic disorders, including type 2 diabetes. Currently Reduxin Forte is registered on the Russian pharmaceutical
The origins of obesity in adults: the role of antenatal and early postnatal periods
Abstract
The extent of the spread and the rate of increase in the incidence of obesity are in the nature of a noninfectious epidemic. Obesity is closely associated with the development of various diseases, including the cardiovascular, digestive systems, the musculoskeletal system,
Diabetes insipidus: disease at the junction of specialties
Abstract
The most common causes of diabetes insipidus are neurosurgical operations on the pituitary gland due to its damage to benign and malignant tumors, neoplasms themselves, lymphocytic hypophysitis. Much less is known about the development of metastatic lesions of the pituitary
Clinical cases
Comorbid patient: diabetic polyneuropathy and cognitive impairments in patient with type 2 diabetes mellitus
Abstract
The pharmacological harmacological treatment of comorbid conditions diagnosed during the course of type 2 diabetes mellitus requires a combination therapy, each component of which must be justified. Personalized approach seems to be most promising. In this article describes
Clinical case of observation of a patient with morbid obesity after bariatric embolization of the left gastric artery
Abstract
The article presents the experience of treating a patient with morbid obesity using bariatric embolization of the left gastric artery - an innovative, minimally invasive method of treating obesity, which demonstrates a decrease in body weight by an average of 18-19% six
Type 1 diabetes mellitus and demyelinating damage to the nervous system
Abstract
The article presents a clinical case of a demyelinating disease in young woman with type 1 diabetes.
In memory of Voychik Emma Anatolievna
Abstracts of Research-to-Practice Conference for Young Scientists of the Russian Medical Academy of Continuous Professional Education «Topical Questions of Endocrinology» (March 20, 2019)
Hypogonadism in males with type 2 diabetes mellitus
Abstract
Type 2 diabetes mellitus (T2DM) and testosterone deficiency are associated with an increased health risk, primarily for the cardiovascular system. We decided to conduct a retrospective study to observe the effect of hypogonadism on the course of T2DM in 40-65 years old men,
The study of the relationship of the initial body weight with gestational increase in puerperas and its effect on the course of pregnancy, childbirth outcomes and risks to the fetus
Abstract
The study analyzed the effect of the initial body weight of a woman and her excessive gestational increase (GIBW) on the incidence of complications of pregnancy and childbirth, fetal health. The study is retrospective. 157 birth histories of women in the postpartum
Clinical and hormonal characteristics of various gonadal dysgenesis variants in girls with hypergonadotropic hypogonadism
Abstract
The aim of this study is to evaluate clinic-laboratory characteristics of various types of gonadal dysgenesis in girls with hypergonadotropic hypogonadism. According to the results of this study the following nosological types of gonadal dysgenesis in girls with
Metabolic syndrome: the innovation approach in diagnostics
Abstract
Metabolic syndrome (MS) is a condition associated with impaired metabolic processes. The main value of MS is to identify individuals at increased risk of developing type 2 diabetes and atherosclerotic cardiovascular diseases. An indicator was found that meets the criteria
The frequency of diagnosis and features of heart failure in type 2 diabetes mellitus
Abstract
The relevance of the study of chronic heart failure in patients with type 2 diabetes is due to the wide prevalence of these diseases, as well as the fact that DM 2 is associated with an increased risk of developing CHF. As is known, DM is an independent risk factor for the
Influence of bariatric embolization of the left gastric artery on the metabolic health of patients with obesity
Abstract
The prevalence of overweight and obesity is growing rapidly in the modern world. Currently more than 250 million people are obese (7% of the population), over 1 billion people are overweight (>30% of the population). By 2025, according to World Health Organization experts
Etiological structure of disorders of sex development 46,XY
Abstract
Aim - to study the structure of disorders of sex development (DSD) 46,XY. Material and methods. It was included 57 patients with DSD 46,XY. All children evaluated the structure of the external and internal genitalia, hormonal evaluated. There was removed from 23 gonads of 15
Role and functions of melatonin
Abstract
Melatonin is the hormone of the pineal gland, which is produced with night / day rhythm and is the main regulator of circadian rhythms. Darkness is the main factor contributing to its synthesis. In this context, the problem of light pollution is of particular relevance.
Primary adrenal insufficiency. Clinical case
Abstract
Primary chronic adrenocortical insufficiency is a rare disease, characterized by non-pathogenic symptoms and slow progression. Usually this disease is hidden under the masks of other pathologies. In this clinical case presented a typical symptom complex, diagnostic search
International practice
Hypothyroidism in the older population
Abstract
Background . Both overt hypothyroidism as well as minor elevations of serum thyrotropin (TSH) levels associated with thyroid hormones within their respective reference ranges (termed subclinical hypothyroidism) are relatively common in older individuals. There is growing
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