Topic number
2 . 2020
Content
Editorial

VI International Scientific Congress “Globalistics-2020: Global Problems and the Future of Humanity”

Abstract
The Russian Medical Academy of Сontinuing Professional Education takes part in the VI International Scientific Congress «Globalistics-2020: Global Problems and the Future of Humanity», which started on May which started online on May 20, 2020. The Congress in

The complexity of choosing antihyperglycemic drugs to patients with COVID-19

Abstract
Coronavirus disease has corrected modern life. When someone with diabetes falls ill with COVID-19, a very severe case. Diabetes is accompanied by obesity, diseases of the cardiovascular system, kidneys. It adversely affect the outcome of an infectious disease. That is why,

Dear colleagues!

Abstract
Original research

Changes in SGLT2i and GLP-1RA real-world initiator profiles following cardiovascular outcome trials: A Danish nationwide population-based study

Abstract
Background. We investigated changes in clinical characteristics ofSGLT2i and GLP-1RA real-world initiators in Denmark before/after landmark cardiovascular outcome trials. Methods. We compared first-time SGLT2i (25 070) and GLP-1RA (14671) initiators to initiators of DPP-4i (

Complex therapy of diabetic polyneuropathy taking into account endothelial dysfunction in patients with type 2 diabetes mellitus

Abstract
The aim of the study is to assess the functional state of the endothelium in patients with type 2 diabetes after complex therapy with drugs of alpha-lipoic acid, vitamin B 12 , cocarboxylase, ATP and nicotinamide. Material and methods. The study involved 24 patients aged 45

Advantages of long-term management the metabolic health in patients with obesity and early disorders of carbohydrate metabolism

Abstract
The current task of modern endocrinology is still to find the optimal therapeutic approach that increases the effectiveness of managing the metabolic health in patients with obesity and early disorders of carbohydrate metabolism. Monotherapy with drugs registered in Russia
Reviews

Dulaglutide, a glucagon-like peptide-1 receptor agonist: in the search for survival molecule

Abstract
Cardiovascular diseases are the Leading cause of mortality and a decline in the quality of Life in patients with T2DM. Therefore, multifactorial management is the basis of a strategic approach to the treatment of diabetes. Its basic principles include: control of glucose,

Role of sodium-glucose co-transporter type 2 inhibitor dapagliflozin in prevention of cardiovascular complications in patients with diabetes mellitus type 2

Abstract
Medical science is shaping more complex approach to health. One example of this trend is helping a patient with type 2 diabetes. Against the background of increasing life expectancy, the spread of metabolic disorders, cardiovascular diseases and renal dysfunction

The role and point of the disturbed redox balance in the development of diabetic neuropathy and antioxidant effects of alpha-lipoic acid

Abstract
The article provides an analytical review of studies describing the mechanisms of disturbances in the redox balance of an organism under hyperglycemia, and their influence on the occurrence and progression of diabetic neuropathy, as well as the point and role of antioxidants
Clinical cases

Current tendencies in treatment of congenital hypogonadotropic hypogonadism in boys: clinical cases’ analysis

Abstract
This article includes analysis of clinical cases of isolated congenital hypogonadotropic hypogonadism and hypogonadism due to hypopituitarism in boys. We evaluated the timeliness of diagnosis and therapy onset and effectiveness of combination therapy with recombinant
Proceedings of the XI scientific and practical conference of young scientists with international participation “Translational Medicine: possible and real” (Moscow, April 2–3, 2020)

Dear readers!

Abstract

The effect of circadian rhythm disturbance on carbohydrate metabolism and the severity of obesity in patients with type 2 diabetes mellitus

Abstract
In this work, we analyzed the effect of the disturbed circadian rhythm on carbohydrate metabolism and on the severity of obesity in patients with type 2 diabetes mellitus. Patients with type 2 diabetes mellitus working in night shifts were presented as a model of patients

A cohort study: endocrinologist’s physical active pattern

Abstract
Medical health worker's physical activity (PA) is a strong predictor of their propensity for lifestyle therapy consulting. The aim of this study was to evaluate endocrinologist's PA level and their motivation to more active lifestyle. We have performed a survey that included

Assessment of metabolic disorders in patients with prostate cancer receiving luteinizing hormone-releasing hormone agonists

Abstract
Therapy with luteinizing hormone-releasing hormone agonists (aLHRH) is the main method of androgen-deprivation therapy (ADT) for prostate cancer (PCa). Such therapy is accompanied by side effects: sarcopenia, metabolic disorders, osteoporosis, etc. This study is devoted to

Pharmacogenetic testing of the gluccorticoid receptor and cytochrome P450 gene in patients with endocrine ophthalmopathy

Abstract
For more than 50 years, glucocorticoid therapy has been practically the only method for treating patients with endocrine ophthalmopathy. There are steroid-resistant forms of this disease, the frequency of which ranges from 4-5%. There is evidence that one of the reasons for

Puberty delay in girls: analyses of disease structure depending on clinical characteristics

Abstract
The aim of this study was to evaluate the structure of puberty delay in girls according to clinical characteristics. Results of this study showed the association between permanent or transient puberty delay in girls and clinical signs of illness. Permanent puberty delay was

Difficulties in diagnosing insulinoma

Abstract

Insulinoma is harmonally active tumor of pancreatic, resulting hypoglycemia. Hypoglycemia often leads to brain dysfunction. That is why neurology symptoms is the first, and diagnostic is very difficult.

Modern methods of diagnosis of the ophthalmic complications of acromegaly

Abstract
Acromegaly is a rare disorder that can cause chiasmal syndrome. Compression of the optic chiasm due to the growth of pituitary adenoma leads to various visual problems manifesting mainly as bitemporal hemianopsia (loss of lateral vision in both eyes). Acromegaly patients

Prevention of type 2 diabetes at the pre-diabetes stage

Abstract
The growing pandemic of diabetes poses an enormous public health challenge for almost every country across the globe. Prevention of type 2 diabetes is a major concern in many countries around the world. We have described the basic principles for the prevention of type 2

The role of natural Siberian fir terpenoids in the prevention of dyslipidemia in patients with type 2 diabetes

Abstract
The article provides a review of domestic and foreign literature on the role of natural terpenoids in the correction of dyslipidemia in patients with type 2 diabetes. Discusses the causes and complications development of type 2 diabetes in the form of dyslipidemia from the

Some aspects of eating behavior and physical performance in overweight adolescents

Abstract
In obese and overweight adolescents and adolescents with a normal body mass index, a questionnaire was conducted using the DEBQ test questionnaire: "Types of eating disorders", the maximum treadmill test according to the Bruce Protocol, assessing the nature of nutrtion. The
Tests

Test preparation under the “Moscow Doctor” Programme. Thyroid disorders: hypothyroidism

Abstract

Test preparation under the “Moscow Doctor” Programme. Thyroid disorders: thyrotoxicosis

Abstract
News

News (# 2, 2020)

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Announcements

Announcemets (# 2, 2020)

Abstract

All articles in our journal are distributed under the Creative Commons Attribution 4.0 International License (CC BY 4.0 license)

CHIEF EDITOR
CHIEF EDITOR
Ametov Alexander S.
Honored Scientist of the Russian Federation, Doctor of Medical Sciences, Professor, Head of Subdepartment of Endocrinology, Head of the UNESCO Network Chair on the subject «Bioethics of diabetes as a global problem» of the Russian Medical Academy of Continuous Professional Education (Moscow)
Вскрытие

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