Topic number
3 . 2020
Metabolic disorders: therapy
Content
Editorial

Anniversary Congress of the American Diabetes Association (ADA 2020): what's new in diabetology

Abstract
This year, for the first time in its 80-year history, the Congress of the American Diabetes Association (ADA 2020) was held entirely online. Scientists demonstrated data from several clinical studies of the latest automated insulin delivery systems. Recommendations on

ADVANCE study - 20 years later

Abstract
A crucial point in the long-term, effective and safe management of type 2 diabetes is the data from clinical studies that allow us to make the right choice in favor of a particular drug. The results of the ADVANCE study demonstrated that taking gliclazide MR leads to a
Original research

The effect of the sodium-glucose cotransporter-2 inhibitors in combination with metformin on various metabolic health parameters of patients with type 2 diabetes and visceral obesity

Abstract
The aim - to assess the effect of canagliflozin and metformin therapy on carbohydrate and fat metabolism in patients with type 2 diabetes and visceral obesity. Material and methods. The study 35 patients with type 2 diabetes and visceral obesity with poor glycemic control.

Clinical features and outcomes of recalcitrant ulcers in diabetic foot patients: a retrospective cohort study

Abstract
The aim of this study was to evaluate the proportion, clinical characteristics and outcomes of recalcitrant diabetic foot ulcers in a diabetic foot department. Material and methods . This is a retrospective cohort study of diabetic foot patients from the specialized

Predictors of acromegaly clinical history and treatment effectiveness (based on Moscow Register Data)

Abstract
Acromegaly is a severe multi-organ disease that negatively affects the quality and life expectancy of patients. The continuing complexity of curation of acromegaly is due to the multiplicity of pathomorphological variants of growth hormone-secreting adenomas, which differ in

Some physical and hormonal parallels in boys of puberty (on the model of the Republic of Dagestan)

Abstract
The aim of this study was to analyze the indicators of physical development of boys (BMI) and their influence on the hormonal status that characterizes sexual development (levels of LH, FSH, testosterone) in 2 age groups. The first group consisted of boys of the early
Reviews

Taurine is an amazing molecule in controlling metabolic syndrome

Abstract
Metabolic syndrome, a cluster of risk factors for diabetes and cardiovascular disease, has become a very serious public health problem. A number of studies indicate that taurine has an effect on the components of the metabolic syndrome, including lowering total cholesterol,

Modern approaches to the diagnosis and treatment of diabetic polyneuropathy

Abstract
Diabetic neuropathy is the most common complication of diabetes mellitus and is characterized by symmetric damage of nerve fibers, usually slow and irreversible progression. Early diagnosis and timely treatment based on blocking the main pathogenetic mechanisms can slow the
Clinical cases

Latent presarcopenic obesity in a patient with inflammatory bowel disease

Abstract
Sarcopenia is a pathological condition that manifested by a general, progressive decrease in skeletal muscle mass, muscle strength and performance, which leads to weakness, impairs quality of life and increases the risk of death. Previously, sarcopenia was only prevalent in
Proceedings of the XI scientific and practical conference of young scientists with international participation “Translational Medicine: possible and real” (Moscow, April 2–3, 2020)

Endocrine components of Kearns-Sayre syndrome: underweight 21-year-old female patient with diabetes mellitus, primary amenorrhea, and secondary hyperparathyroidism

Abstract
Kearns-Sayre syndrome is an inborn defect of metabolism caused by a mitochondrial DNA (mtDNA) deletion. In addition to neurological and cardiological manifestations such endocrine disorders as hypogonadism, diabetes mellitus, hypothyroidism, hypoparathyroidism, adrenal

The relationship between carbohydrate metabolism and glycemias variability in patients with type 2 diabetes working in night shifts

Abstract
The paper analyzes the parameters of carbohydrate metabolism and glycemic variability in people with type 2 diabetes who work night shifts. The study was conducted on train drivers who were presented as models of patients with impaired circadian rhythm. The simulation of

Sodium-glucose cotransporter 2 inhibitors in lipotoxicity correction Gogoleva S.P.

Abstract
Adipokines are involved in the regulation of almost all processes in the body. Their production impairment and excessive accumulation of free fatty acids lead to the development of lipotoxicity. Sodium-glucose cotransporter-2 (SGLT2) inhibitors may affect both carbohydrate

Credibility of FRAX results in women with recurrent fractures according to clinical practice

Abstract
This research is devoted to analysis the presence of risk factors (RF) for the development of osteoporosis in patients aged 48 to 88 with a previous history of low-energy fractures (LF), estimat the 10-year probability of developing LF and the threshold of therapeutic

Estimation of efficiency and safety of use SGLT2 inhibitors and glucagon-like peptide agonists among patients with diabetes and cardiovascular disease in clinical practice

Abstract
This study is devoted to assessing the efficacy and safety of the use of drugs from the iNGLT-2 group and AR GLP-1 in the treatment of type 2 diabetes in patients with in patients with cardiovascular diseases (CVD) and the effect of the group of iNGLT-2 group and AR GLP-1 on

Puberty delay in girls: etiologic structure of the disease

Abstract
The aim of this study was to evaluate the etiological structure of puberty delay in girls. Results of this study showed that puberty delay structure in girls includes the equal proportions of transient and permanent hypogonadism cases. Permanent hypergonadotropic

Metabolic adverse effects of immunosuppressive drugs after solid organ transplantation: current stage of known problem

Abstract

Understanding of hyperglycemia development mechanisms on current immunosuppressive treatment is necessary to choose the desirable antidiabetic therapy.

Metabolic outcomes in obesity patients after bariatric embolization of the left gastric artery

Abstract
In this work, we present the experience of treating patients with morbid obesity before and after bariatric embolization of the left gastric artery. Against the background of the treatment, there is a statistically significant decrease in weight, BMI, a decrease in the level

Long-term effect of paraaortic irradiation on adrenal function

Abstract
The use of modern comprehensive treatment programs for Hodgkin lymphoma leads to the complete cure of most patients. However the methods used have a number of side effects, some of which appear years later.In order to assess the functional state of the adrenal glands, 27
Tests

Test preparation under the “Moscow Doctor” Programme. Thyroid diseases: endocrine ophthalmopathy

Abstract
У важаемые коллеги, мы продолжаем рубрику "Подготовка к тестовому контролю по программе "Московский врач" (специальность 14.01.02 "Эндокринология") для ознакомления врачей-эндокринологов с тестовыми заданиями по разным разделам клинической эндокринологии. В этом номере

Test preparation under the “Moscow Doctor” Programme. Thyroid diseases: thyroid cancer

Abstract

Test preparation under the “Moscow Doctor” Programme. Thyroid diseases: thyroiditis

Abstract
News

News (# 3, 2020)

Abstract
Announcements

Announcements (# 3, 2020)

Abstract

All articles in our journal are distributed under the Creative Commons Attribution 4.0 International License (CC BY 4.0 license)

CHIEF EDITOR
CHIEF EDITOR
Ametov Alexander S.
Honored Scientist of the Russian Federation, Doctor of Medical Sciences, Professor, Head of Subdepartment of Endocrinology, Head of the UNESCO Network Chair on the subject «Bioethics of diabetes as a global problem» of the Russian Medical Academy of Continuous Professional Education (Moscow)
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