Topic number
4 . 2020
90 years of the Russian Medical Academy of Continuous Professional Education
Content
Editorial

Botkin readings on bioethics, ethics of science and ethics of artificial intelligence in the context of COVID-19

Abstract
Within the framework of the VI International Scientific Congress “Globalistics-2020: Global issues and the future of humankind” under the official auspices of UNESCO an international online conference “Botkin readings on bioethics, ethics of science and

To the anniversary of Elvira P. Kasatkina

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Original research

Glucose homeostasis and metabolic flexibility in healthy individuals

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Multifactorial management of type 2 diabetes implies a close approximation to normal physiology. This article presents an analytical review of the literature on glucose homeostasis and metabolic flexibility in healthy individuals under various conditions, as well as the

Integrated evaluation possibilities of man’s hypothyroidism pathogenetic effect on erectile dysfunction forming

Abstract
The article is devoted to the thyroid gland pathology in the spreading of different sexual disorders in male population. The aim of research – to study the occurrence frequency of decreased thyroid hormones level among the patients with erectile dysfunction (ED) and to
Reviews

Possibilities of pharmacokinetic modeling on the example of Diabeton MR (Diamicron MR): point of view of an endocrinologist and pharmacologist

Abstract
The differences between the individual sulfonylurea medicines (SUs) are determined by pharmacokinetic properties such as absorption rate and completeness, elimination half-life, and the participation of hepatic and renal elimination mechanisms from the body. The

Features of prevention and complex rehabilitation in diabetic foot syndrome

Abstract
The topic of this article is devoted to the problems of diabetic foot syndrome, its etiology and pathogenesis of its development. Also economic and social aspects of this complication of diabetes are shown. Particular attention is paid to prevention, medical and social

Male hyperestrogenism. Artificial problem or existing reality? Are aromatase inhibitors effective and safe?

Abstract
One of the global medical problems of today, besides obesity, type 2 diabetes mellitus and cardiovascular diseases, is the problem of testosterone deficiency in men, which develops at a pretty young age. Often, under the absolute lack of testosterone masked excess activity

Evolution of continuous glucose monitoring in existing clinical guidelines for patient with diabetes mellitus

Abstract
Assuming the dramatic growth in the number of patients with diabetes mellitus, their adherence to enough glycemic control is crucial. The number of patients utilizing new technologies to control their disease, including continuous glucose monitoring, is now increasing. Flash

Antioxidant effect of alpha-lipoic acid and possibility for its use in the treatment of diabetic autonomic neuropathy

Abstract
Russian Medical Academy of Continuing Professional Education, 125993, Moscow, Russian Federation The article provides an overview of studies describing the mechanisms of the antioxidant action of alpha lipoic acid, as well as the results obtained with its use in the
Clinical cases

Bioimpedance analysis: clinical cases and explanation of changes in human body composition under the influence of various factors

Abstract
The article presents clinical cases of effective control of changes in human body composition under the influence of certain factors using one of the most accessible objective methods for assessing body composition – bioimpedance analysis. The article consists of a

Management of type 2 diabetes mellitus. Approaches to pathogenetic therapy

Abstract
This clinical case shows the positive effects of adding alogliptin (Vipidia®) to metformin monotherapy on carbohydrate metabolism, lipid profile and body composition, muscle-fat ratio without significant weight dynamics. Knowing the positive effects of GLP-1 on fat
Proceedings of the XI scientific and practical conference of young scientists with international participation “Translational Medicine: possible and real” (Moscow, April 2–3, 2020)

Type 2 diabetes mellitus and risk factors for cardiovascular disease. The advantage of choosing drugs iSGLT-2 and arGPP-1

Abstract
The aim of the study was to evaluate the effect of drugs SGLT-2 or arGPP-1 on the treatment of type 2 diabetes in patients with cardiovascular risks. As a result of the study, it was found that drugs of the SGLT-2 and arGPP-1 are especially attractive due to their positive

Assessment of the actual nutrition of women with diabetes: are there any differens from “healthy” women?

Abstract
Material and methods. A comparative assessment of the actual nutrition of 58 women: without a violation of carbohydrate metabolism (group 1, n =35) and with diabetes (group 2, n =23), with the use of the computer program “Analysis of human nutritional status (version 1

Usage of pump insulin therapy in treatment of patients with type 1 diabetes

Abstract
This work is devoted to the study of efficiency of pump insulin therapy for patients with type 1 diabetes. The study showed, that the use of pump insulin therapy for treating patients with type 1 diabetes allows to decrease daily dose of insulin, lowers variability and

Complex therapy of the sensory form of diabetic neuropathy

Abstract
The article discusses the effect of complex therapy on the severity of the sensory form of diabetic neuropathy in patients with type2 diabetes mellitus. As a result, it was shown that the complex therapy of diabetic polyneuropathy leads to a significant regression of its

Deprescribing of anti-diabetic medicines in the elderly and senile age people with type 2 diabetes mellitus

Abstract
The aim of this study is evaluate the safety and efficacy to stop or switch to another antidiabetic drugs in elderly and senile people with type 2 diabetes. As a result of the study, against the background of the correction of glucose-lowering therapy, all patients noted

Effects of the combination metformin and iSGLT-2 in clinical use

Abstract
The research is devoted to the study of the effects of a combination of drugs metformin and iSGLT-2 on the treatment of type 2 diabetes. Initial combination treatment with an iSGLT2 inhibitor and metformin shows high efficacy, results in a clinically meaningful and

Insulin resistance – significance in the pathogenesis of metabolic syndrome

Abstract
Insulin resistance – failure of the biological respond to insulin, carbohydrate, fat and protein metabolism, as well as variation of the DNA synthesis, changes in cell and tissue differentiation and growth process. Insulin resistance detected in those patients with

Early сarbohydrate metabolism disorders and their impact on cardiovascular risks

Abstract

The study focuses on the impact of early carbohydrate metabolism disorders on cardiovascular risks. The study revealed these risks in individuals with impaired carbohydrate metabolism, compared with the control group.

Tests

Test preparation under the “Moscow Doctor” Programme. Thyroid diseases: thyroid gland and pregnancy hypothyroidism, thyrotoxicosis), amiodarone-induced thyropathies

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CHIEF EDITOR
CHIEF EDITOR
Ametov Alexander S.
Honored Scientist of the Russian Federation, Doctor of Medical Sciences, Professor, Head of Subdepartment of Endocrinology, Head of the UNESCO Network Chair on the subject «Bioethics of diabetes as a global problem» of the Russian Medical Academy of Continuous Professional Education (Moscow)
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