Editorial
Original research
Vitamin D deficiency: gender characteristics
Abstract
Studies assessing vitamin D status are relevant both in the world and in the Russian Federation to determine the frequency of 25(OH)D deficiency, the severity of vitamin D metabolism disorders and focus populations with the greatest problems in vitamin D supply. We have
Assessment of the variability of glycemic levels based on self-control. Pilot project results
Abstract
Modern approaches to the treatment of type 1 diabetes mellitus (DM) involve assessing the quality of glycemic control by the Level of glycated hemoglobin (HbA1c). However, in recent years, it has become important to assess the variability of glycemia (GV) as an independent
Diabetes mellitus and COVID-19 in Moscow: status 2020
Abstract
Against the backdrop of the COVID-19 pandemic, there is an increase in the number of deaths among the population of all countries. At the same time, separate groups of patients are distinguished, the mortality rate in which significantly exceeds the average. Patients with
The prevalence of hyperestrogenism and testosterone deficiency in obese men
Abstract
Currently, there is practically no epidemiological data on the incidence of hyperestrogenism, and it is still indirectly estimated by the prevalence of gynecomastia. The aim of our work was to assess the prevalence of hyperestrogenism, androgenic deficiency and the
Reviews
Modern classifications of pituitary neuroendocrine tumors
Abstract
This review is devoted to the discussion of new trends in the identification of pituitary tumors and the assessment of the prospects of modern morpho-functional and prognostic classifications that ensure the implementation of a personalized approach to the treatment of
Relationship between obesity and hypertension: how can the effect on appetite reduce blood pressure?
Abstract
Over the past half century, there has been a rapid increase in the number of cases of obesity, due to a significant change in lifestyle. First of all, this can be attributed to the easy availability of high-calorie foods and a decrease in physical activity. So, according to
Glyclazide MR: obvious benefits
Abstract
Sulfonylureas are effective oral hypoglycemic agents that have been used for a long time in clinical practice. Although they all share a common mode of action, their pharmacokinetic and pharmacodynamic properties are influenced by dosage, absorption rate, duration of action,
Simple, effective and convenient regime for treatment of type 2 diabetes mellitus
Abstract
According to the data currently in the world, there are about half a billion patients with diabetes mellitus, 90% of which is type 2 diabetes. Equally disturbing is the fact that there are 250 million people with unidentified type 2 diabetes and more than 300 million with
Complex metabolic protection as a modern strategy for the management of type 2 diabetes mellitus
Abstract
The primary task of managing patients with type 2 diabetes meLLitus is complex cardiometabolic protection, which can be implemented by including innovative drugs in therapy: agonists of glucagonlike peptide-1 receptors and inhibitors of type 2 sodium glucose cotransporter.
Clinical cases
Management of cardiorenal risks in patients with type 2 diabetes mellitus
Abstract
This clinical case demonstrates the benefits of using the sodium-glucose cotransporter type 2 inhibitor empagliflozin in combination therapy with metformin in a patient with type 2 diabetes mellitus and high cardiovascular and renal risks in routine clinical practice. The
Features of differential diagnosis of diabetes mellitus in the modern world: clinical observation
Abstract
In this review, a clinical case of diabetes in a young patient demonstrates atypical diseases and diagnostic difficulties. Diabetes mellitus is a heterogeneous group of diseases characterized by persistently elevated blood glucose levels. Although diabetes mellitus type 1
Multiple endocrine neoplasia type 1 syndrome: causal factors that make timely diagnosis difficult
Abstract
Multiple endocrine neoplasia syndrome of the first type (MEN-1) is a genetically determined disease with an autosomal dominant type of inheritance, characterized by a tumor lesion of the parathyroid glands, pancreas and anterior pituitary gland. Skin manifestations in the
The role of various forms of vitamin D in the treatment of patients with vitamin D deficiency (clinical case)
Abstract
Currently, vitamin D deficiency is widespread. This deficiency can be masked as manifestations of asthenia and remain undiagnosed. For various reasons, many patients self-medicate, as demonstrated in the description of the clinical case. A misconception is the safety of the
То practitioner’s consult. Time in range
Flash glucose monitoring in the practice of pediatric endocrinologist
Abstract
Continuous glucose monitoring technologies are rapidly gaining positions in pediatric endocrinology practice: according to foreign authors, the number of children using continuous glucose monitoring (CGM) technologies increased 10-fold from 2016 to 2018. In the Russian
Tests
Proceedings of the XII Scientific and practical conference of young scientists with international participation “Translational medicine: possible and real”
Infection index and quality of life parameters in patients with metabolic syndrome
Abstract
The aim of this study was to research of the infectious index and quality of life parameters in patients with metabolic syndrome. Results of this study showed that the infectious morbidity in patients with metabolic syndrome against the background of taking a complex of
The prevention of iodine deficiency in children living in an ecologically contaminated area by using organic compounds of iodine and selenium
Abstract
A study of the prevention of iodine deficiency in children living in an ecologically contaminated area was carried out. The ways of solving this problem were investigated. It is established that the use of organic compounds of iodine and selenium contribute to normalization
Markers of inflammatory response and blood coagulation disorders in patients with type 2 diabetes and COVID‑19
Abstract
This study compared coagulation dysfunction and inflammatory status between diabetic and non-diabetic patients with COVID-19 pneumonia. The levels of C-reactive protein were higher in patients with type 2 diabetes, regardless of the severity of pneumonia on CT, but this
Endothelial dysfunction on the background of hypothyroidism is the main factor in the erectile dysfunction formation at the comorbid pathology
Abstract
Lipid metabolism levels and plasma markers of endothelial dysfunction (ED) among patients with vasculogenic erectile dysfunction (VED) on the background of hypothyroidism and euthyroidism have been studied to assess the frequency of ED formation in these disorders. Men with
Cognitive impairment epidemiology in elderly with type 2 diabetes mellitus
Abstract
According to current guidelines screening for cognitive impairment (CI) is necessary in patients with diabetes mellitus type 2 over the age of 65 years. In this cross-sectional study we enrolled 135 patients with average age of 71.5 (68-77) and diabetes duration 13.0 (10-20)
Sarcopenia, daily activity and nutritional status of elderly patients with type 2 diabetes mellitus: a cohort study
Abstract
Sarcopenia is a condition characterized by progressive and generalized loss of skeletal muscle mass and function. In this crosssectional study we enrolled 151 patients with average age of 71 [68,0; 75,0]. Recruitment performed between December 2019 and March 2021. We used
Dynamics of ejaculate quality indicators associated with reduced body weight in young infertile men with visceral obesity
Abstract
Considering the role of visceral obesity in the development of male infertility, it is relevant to assess the ejaculate quality indicators and the possible connection with a decrease in body weight, which in our work was achieved only because of lifestyle changes. Also the
Clinical and laboratory characteristics of constitutional delayed puberty in girls
Abstract
The aim of this study was to evaluate the clinical-laboratory characteristic of constitutional puberty delay in girls presented by primary amenorrhea in 83.3% of cases. Girls of this group in 90% of cases had average growth rates, in 20% - excess body weight. In all clinical
Thyroid protection during external beam radiotherapy and systemic radioisotope therapy
Abstract
After neck irradiation, some thyroid diseases such as hypo-, hyperthyroidism, or thyroid tumors, including thyroid cancer can occur. As cancer therapy has been improved nowadays and survival rates among the patients have increased, a prevention of longterm adverse effects of
The use of pegvisomant in the complex treatment of acromegaly. Cases from practice
Abstract
The paper discusses rational schemes of pharmacotherapy for acromegaly and the place of pegvisomant in the complex drug treatment of patients with aggressive disease. The first domestic results of the use of pegvisomant, as well as cases from the clinical practice of
Is obesity rather than the dietary supplement used for weight reduction the cause of liver injury?
Abstract
Acute Liver injury has been attributed to dietary supplements (DS) used for weight Loss, but their causal role was much questioned, and obesity as an alternative cause of the liver injury remained unclear. A comprehensive search of the Medline database was conducted with
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