Topic number
3 . 2013
Diabetes and other endocrine disorders
Content
Editorial

Editorial

Abstract
News of endocrinology

News of endocrinology

Abstract
Endocrinology history

Diabetes mellitus and insulin

Abstract
Reviews

Cardiovascular safety of antihyperglycemic therapy intensification

Abstract
Type 2 diabetes mellitus is a chronic, advanced disease that can lead to development of vascular events that in turn can significantly increase risk of cardiovascular mortality. However some researches prove importance of glycemic control for decreasing the risk of diabetic

Old diseases in modern light: hypercortisolism devoid of specific clinical symptoms

Abstract
In this review there are discussed modern concepts concerning Cushing Syndrome/ syndrome of hypercortisolism, which is actual for internists. There are mentioned data on emergence of "new" forms of Cushnig syndrome, the increasing occurrence of clinically erased forms of

Effectiveness of alpha-lipoic acid in diabetic polyneuropathy

Abstract
The data obtained so far testify to the effectiveness of intravenous induction and tableted administration of alpha-lipoic acid by patients with distal symmetric mixed sensory motor neuropathy. It affects on pathogenetic mechanisms of alpha-lipoic acid synthesis and improves

Justifications for taurine application in case of diabetes mellitus and its complications (Russian clinical experience)

Abstract
Diabetes mellitus (DM) according to its prevalence and complications becomes rampant. Constantly appear or improved methods of treatment of patients – medicines and methods of control of blood glucose. The biological function of taurine, opened in the beginning of the

Modern approaches to diagnostics, treatment and monitoring of age-related androgen deficiency in men (clinical lecture)

Abstract
Diabetes is one of the most common chronic diseases in the world. And today one of the major risks facing patients with diabetes mellitus are its complications and high level of invalidization and mortality rate. We are talking about: diabetic retinopathy, diabetic

Estimation of correlation between adipokines and parameters of carbohydrate and lipid metabolism in patients with acromegalia

Abstract
Akromegaliya is a serious neuroendocrine desease caused by chronic hyperproduction of somatotropic hormone. At this pathology abnormality of different metabolic types is observed. Adipose tissue release a large number of adipokines that can influence on insulin sensitivity.

Problems in glycemic control among patients with type 2 diabetes mellitus receiving insulin therapy (part 2)

Abstract
Injection techniques for patients with type 2 diabetes mellitus pack a punch on therapeutic properties of medicament. The huge number of cover one's mistakes and problems observed in group of patients receiving insulin, was because of lack of knowledge and skills for correct
Original research

Does severe hypoglycaemia influence microvascular complications in type 1 diabetes? An analysis of the Diabetes Control and Complications Trial database

Abstract
Aims. Severe hypoglycaemia may have a role in aggravating micro- and macrovascular disease in diabetes. Data from the Diabetes Control and Complication Trial have been reanalysed to ascertain whether the frequency of severe hypoglycaemia exerted an influence on the

Features of a hormonal metabolism in men with diabetes mellitus type 2 and coronary heart disease

Abstract
81 men ranged in age from 40 to 81with ischemic heart disease, type 2 diabetes mellitus and both were examined. Significant hypotestosteronemia was revealed and it was fixed its influence at insulin resistance and atherogenic dislipidemy formation. The survey has found that

Role and place of fenofibrate in complex multifactorial therapy of diabetic peripheral neuropathy in patients with type 2 diabetes mellitus

Abstract
Diabetic peripheral neuropathy (DPN) is one of the most common chronic complications of diabetes mellitus leading to deterioration of the patients’quality of life. Effective methods for the treatment of DPN and improvement of both quality of life and long-term

Multicenter study of the prevalence of blood contamination on point-of-care glucose meters and recommendations for controlling contamination

Abstract
This study is the first conducted to characterize the prevalence of blood contamination on hospital glucose meters, which potentially may spread infection. Twelve academic and nonacademic affiliated hospitals participated in hospitalwide surveys for blood contamination on

Features of adaptive capacity and energy metabolism in patients with diabetes mellitus type 2

Abstract
Aims: There is limited evidence regarding the association between physical activity and vascular complications, particularly microvascular disease, in patients with type 2 diabetes. Methods: From the 11 140 patients in the ADVANCE (Action in Diabetes and Vascular Disease:

Distance tele-education based on professional video conferencing systems

Abstract
Distance teleeducation of medical personal allows to adopt specialists experience of the leading federal medical centers, to master new diagnostics and treatment methods and monitor all medical innovations. Besides it facilitate lectures on the separate problems that are
Abstracts of reports

Role of the lipotoxicity in glycemic control achieving

Abstract
Objective: To improve management of type 2 diabetes mellitus by influencing of the lipotoxicity. Materials and Methods: The study involved 77 patients with type 2 diabetes mellitus with bad glycemic control (HbA1c 7,5–11%) on OADs prior therapy.Along OADs treatment,

Evaluating the effectiveness of early dipeptidylpeptidase-4 inhibitors combined therapy for type 2 diabetes mellitus

Abstract

The effectiveness of ingibitors of dipeptidylpeptidazy type 4 in combination with metformin in patients with type 2 diabetes mellitus and obesity

Abstract

The effect of derivative bicyclic bisurea on lipid metabolism in patients with angina FC I-III

Abstract

Application of complex immunomodulatory therapy in treatment of nodular goiter

Abstract

The assessment of the small intestine parietal microbiota in patients with chronic pancreatitis

Abstract
The frequency of small intestine bacterial overgrowth in chronic pancreatitis exceeds half of all the cases. Therefore, the definition and correction of small intestine microbiota’s changes is necessary action in complex therapy of this disease. The modern method of

The role and place of continuous glucose monitoring in multivariate control of type 2 diabetes

Abstract
Objective: To assess the role and place of the continuous glucose monitoring in the management of type 2 diabetes mellitus(T2DM). Materials and Methods: The study enrolled two groups of patients with T2DM on therapy with oral antidiabetic drugs. 1st group included 60

Cardiovascular risks in patients with type 2 diabetes mellitus and obesity

Abstract
Objective: To assess the impact of variability of blood glucose in patients with type 2 diabetes mellitus and hypertension on indicators of cardiovascular risk in patients receiving the drug reduxine and weight loss. Materials and Methods: The study included 80 patients. 50

Glycemic control and variability of blood glucose in patients with type 2 diabetes mellitus managed with sulfonylureas, the DPP -4-inhibitors

Abstract
Objective: to assess the glycemic control and variability of daily blood glucose of low-dose DPP-4 inhibitor saxagliptin and sulfonylurea (gliclazide) as add-on therapy to metformin in patients with inadequate glycemic control with metformin alone and saxagliptin add-on

Role of chronic low-grade inflammation in the development of the complications type 2 diabetes mellitus

Abstract
Aims: The aim of the present study was to investigate role of chronic low-grade inflammation in the development of the complications type 2 diabetes mellitus. Methods: patients with type 2 diabetes mellitus evaluated glycemic and lipid profile, inflammatory cytocines,

Efficacy and safety of sulfonylurea drugs in the patients with type 2 diabetes mellitus in combination with coronary artery disease

Abstract
Objective: to evaluate the efficacy and safety of the use of sulfonylurea drugs in patients with type 2 diabetes mellitus in combination with coronary artery disease. Methods: All patients with stable coronary artery disease and type 2 diabetes mellitus, uncontrolled with

Diabetic gynecomastia: ultrasound criteria

Abstract
Aim: to analyze ultrasound features of gynecomastia in diabetic males. Methods: We analyzed the protocols of complex ultrasound examinations of 480 men of 24–74 years of age, who had gynecomastia and suffered diabetes for more than 3 years. We used S2000 (Siemens

The relationship between erectile function and lipotoxicity

Abstract
Aim: to study the characteristics of clinical and laboratory parameters in obese men. Materials and Methods: the study included 31 men aged 30 to 55 years (mean age 43,7 years). At baseline, all patients had a diagnosis of obesity (BMI30). Mean body mass index was 38

Managment of lipotoxicity and glucosotoxicity in newly diagnosed diabetes type 2

Abstract
Aim: improving the management of newly diagnosed type 2 diabetes by affecting the lipotoxicity and glucosetoxicity. Methods: Patients with newly diagnosed type 2 diabetes evaluated the glycemic and lipid profile, free fatty acids, body composition by dual energy
Clinical cases

Clinical cases

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Announcements

Announcements

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All articles in our journal are distributed under the Creative Commons Attribution 4.0 International License (CC BY 4.0 license)

CHIEF EDITOR
CHIEF EDITOR
Ametov Alexander S.
Honored Scientist of the Russian Federation, Doctor of Medical Sciences, Professor, Head of Subdepartment of Endocrinology, Head of the UNESCO Network Chair on the subject «Bioethics of diabetes as a global problem» of the Russian Medical Academy of Continuous Professional Education (Moscow)
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