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Cardiovascular safety of antihyperglycemic therapy intensification
Abstract
Type 2 diabetes mellitus is a chronic, advanced disease that can lead to development of vascular events that in turn can significantly increase risk of cardiovascular mortality. However some researches prove importance of glycemic control for decreasing the risk of diabetic
Old diseases in modern light: hypercortisolism devoid of specific clinical symptoms
Abstract
In this review there are discussed modern concepts concerning Cushing Syndrome/ syndrome of hypercortisolism, which is actual for internists. There are mentioned data on emergence of "new" forms of Cushnig syndrome, the increasing occurrence of clinically erased forms of
Effectiveness of alpha-lipoic acid in diabetic polyneuropathy
Abstract
The data obtained so far testify to the effectiveness of intravenous induction and tableted administration of alpha-lipoic acid by patients with distal symmetric mixed sensory motor neuropathy. It affects on pathogenetic mechanisms of alpha-lipoic acid synthesis and improves
Justifications for taurine application in case of diabetes mellitus and its complications (Russian clinical experience)
Abstract
Diabetes mellitus (DM) according to its prevalence and complications becomes rampant. Constantly appear or improved methods of treatment of patients – medicines and methods of control of blood glucose. The biological function of taurine, opened in the beginning of the
Modern approaches to diagnostics, treatment and monitoring of age-related androgen deficiency in men (clinical lecture)
Abstract
Diabetes is one of the most common chronic diseases in the world. And today one of the major risks facing patients with diabetes mellitus are its complications and high level of invalidization and mortality rate. We are talking about: diabetic retinopathy, diabetic
Estimation of correlation between adipokines and parameters of carbohydrate and lipid metabolism in patients with acromegalia
Abstract
Akromegaliya is a serious neuroendocrine desease caused by chronic hyperproduction of somatotropic hormone. At this pathology abnormality of different metabolic types is observed. Adipose tissue release a large number of adipokines that can influence on insulin sensitivity.
Problems in glycemic control among patients with type 2 diabetes mellitus receiving insulin therapy (part 2)
Abstract
Injection techniques for patients with type 2 diabetes mellitus pack a punch on therapeutic properties of medicament. The huge number of cover one's mistakes and problems observed in group of patients receiving insulin, was because of lack of knowledge and skills for correct
Original research
Does severe hypoglycaemia influence microvascular complications in type 1 diabetes? An analysis of the Diabetes Control and Complications Trial database
Abstract
Aims. Severe hypoglycaemia may have a role in aggravating micro- and macrovascular disease in diabetes. Data from the Diabetes Control and Complication Trial have been reanalysed to ascertain whether the frequency of severe hypoglycaemia exerted an influence on the
Features of a hormonal metabolism in men with diabetes mellitus type 2 and coronary heart disease
Abstract
81 men ranged in age from 40 to 81with ischemic heart disease, type 2 diabetes mellitus and both were examined. Significant hypotestosteronemia was revealed and it was fixed its influence at insulin resistance and atherogenic dislipidemy formation. The survey has found that
Role and place of fenofibrate in complex multifactorial therapy of diabetic peripheral neuropathy in patients with type 2 diabetes mellitus
Abstract
Diabetic peripheral neuropathy (DPN) is one of the most common chronic complications of diabetes mellitus leading to deterioration of the patients’quality of life. Effective methods for the treatment of DPN and improvement of both quality of life and long-term
Multicenter study of the prevalence of blood contamination on point-of-care glucose meters and recommendations for controlling contamination
Abstract
This study is the first conducted to characterize the prevalence of blood contamination on hospital glucose meters, which potentially may spread infection. Twelve academic and nonacademic affiliated hospitals participated in hospitalwide surveys for blood contamination on
Features of adaptive capacity and energy metabolism in patients with diabetes mellitus type 2
Abstract
Aims: There is limited evidence regarding the association between physical activity and vascular complications, particularly microvascular disease, in patients with type 2 diabetes. Methods: From the 11 140 patients in the ADVANCE (Action in Diabetes and Vascular Disease:
Distance tele-education based on professional video conferencing systems
Abstract
Distance teleeducation of medical personal allows to adopt specialists experience of the leading federal medical centers, to master new diagnostics and treatment methods and monitor all medical innovations. Besides it facilitate lectures on the separate problems that are
Abstracts of reports
Role of the lipotoxicity in glycemic control achieving
Abstract
Objective: To improve management of type 2 diabetes mellitus by influencing of the lipotoxicity. Materials and Methods: The study involved 77 patients with type 2 diabetes mellitus with bad glycemic control (HbA1c 7,5–11%) on OADs prior therapy.Along OADs treatment,
The assessment of the small intestine parietal microbiota in patients with chronic pancreatitis
Abstract
The frequency of small intestine bacterial overgrowth in chronic pancreatitis exceeds half of all the cases. Therefore, the definition and correction of small intestine microbiota’s changes is necessary action in complex therapy of this disease. The modern method of
The role and place of continuous glucose monitoring in multivariate control of type 2 diabetes
Abstract
Objective: To assess the role and place of the continuous glucose monitoring in the management of type 2 diabetes mellitus(T2DM). Materials and Methods: The study enrolled two groups of patients with T2DM on therapy with oral antidiabetic drugs. 1st group included 60
Cardiovascular risks in patients with type 2 diabetes mellitus and obesity
Abstract
Objective: To assess the impact of variability of blood glucose in patients with type 2 diabetes mellitus and hypertension on indicators of cardiovascular risk in patients receiving the drug reduxine and weight loss. Materials and Methods: The study included 80 patients. 50
Glycemic control and variability of blood glucose in patients with type 2 diabetes mellitus managed with sulfonylureas, the DPP -4-inhibitors
Abstract
Objective: to assess the glycemic control and variability of daily blood glucose of low-dose DPP-4 inhibitor saxagliptin and sulfonylurea (gliclazide) as add-on therapy to metformin in patients with inadequate glycemic control with metformin alone and saxagliptin add-on
Role of chronic low-grade inflammation in the development of the complications type 2 diabetes mellitus
Abstract
Aims: The aim of the present study was to investigate role of chronic low-grade inflammation in the development of the complications type 2 diabetes mellitus. Methods: patients with type 2 diabetes mellitus evaluated glycemic and lipid profile, inflammatory cytocines,
Efficacy and safety of sulfonylurea drugs in the patients with type 2 diabetes mellitus in combination with coronary artery disease
Abstract
Objective: to evaluate the efficacy and safety of the use of sulfonylurea drugs in patients with type 2 diabetes mellitus in combination with coronary artery disease. Methods: All patients with stable coronary artery disease and type 2 diabetes mellitus, uncontrolled with
Diabetic gynecomastia: ultrasound criteria
Abstract
Aim: to analyze ultrasound features of gynecomastia in diabetic males. Methods: We analyzed the protocols of complex ultrasound examinations of 480 men of 24–74 years of age, who had gynecomastia and suffered diabetes for more than 3 years. We used S2000 (Siemens
The relationship between erectile function and lipotoxicity
Abstract
Aim: to study the characteristics of clinical and laboratory parameters in obese men. Materials and Methods: the study included 31 men aged 30 to 55 years (mean age 43,7 years). At baseline, all patients had a diagnosis of obesity (BMI30). Mean body mass index was 38
Managment of lipotoxicity and glucosotoxicity in newly diagnosed diabetes type 2
Abstract
Aim: improving the management of newly diagnosed type 2 diabetes by affecting the lipotoxicity and glucosetoxicity. Methods: Patients with newly diagnosed type 2 diabetes evaluated the glycemic and lipid profile, free fatty acids, body composition by dual energy
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