Dapagliflozin induced metabolic health markers dynamics in patients with type 2 diabetes mellitus
Abstract
Sodium-glucose cotransporter type 2 inhibitors (iSGLT2) have demonstrated significant cardio- and renoprotective effects that cannot be explained only by the hypoglycemic effect of these drugs in a number of studies. Thus, it is important to study the effect of this class of
Evolution of the prevalence of the cardiorenal continuum in hospitalized patients with type 2 diabetes in real clinical practice (experience of Moscow City Clinical Hospital No. 52 of Moscow Health Department)
Abstract
It is known that the leading cause of death in patients with type 2 diabetes mellitus (T2DM) is chronic heart failure (CHF), and the leading complication that significantly aggravates the patient’s prognosis is chronic kidney disease (CKD). In this regard, the active
The role of glucagon-like peptide 1 in the remission of type 2 diabetes mellitus in obese patients after metabolic surgery
Abstract
Metabolic surgery has become widespread in recent years due to its high efficiency in the treatment not only of morbid obesity, but also of type 2 diabetes mellitus (T2DM). A decrease in glycemia in patients after bariatric surgery is observed long before a significant
Risk factors and rates of fatal cardiovascular events in patients with extreme and very high risk type 2 diabetes mellitus
Abstract
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in patients with type 2 diabetes mellitus (T2DM). Only a personalized, integrated approach to risk factors (RF) and treatment can improve prognosis and reduce mortality in people with T2DM. The aim
Exploring the possibilities of 3D body scanning for clinical anthropometry and body composition measurement in persons with a high metabolic risk
Abstract
Purpose. T o investigate the possibilities of 3D-scanning for clinical anthropometry and indirect determination of body composition in overweight and obese individuals in comparison with Dual-energy X-ray absorptiometry (DXA). Material and methods . We examined 32 patients
Risk of testosterone deficiency in men with type 2 diabetes depending on the level of glycated hemoglobin
Abstract
Type 2 diabetes mellitus (T2DM) and androgen deficiency are diseases, the combination of which in the patient leads to a significant severity of each of them. There are no data on the critical values of HbA1c levels that provoke the development of testosterone (T) deficiency
Diabetes mellitus and pancreatic cancer: a literature review
Abstract
Diabetes mellitus (DM) and pancreatic cancer (PC) are closely related. The long-term course of DM is considered as a moderate risk factor for the PC development. On the other hand, newly diagnosed DM is often an early symptom of PC. Meta-analyses show a 5–7-fold
Intensification of type 2 diabetes therapy: new accents of traditional approaches
Abstract
Type 2 diabetes mellitus (T2DM) is a common disease, the consequences and complications of which lead to death of thousands. Chronic hyperglycemia significantly increases cardiovascular risk. Mortality from myocardial infarction and cerebral blood flow disorders in patients
Role and place of dulaglutide in type 2 diabetes mellitus management
Abstract
Destructive macro- and microvascular complications of diabetes mellitus lead to an increase of mortality, loss of vision, kidney failure and a an overalldecrease in quality of life. The appearance of GLP-1 receptor agonists (GLP-1 RAs) has become a breakthrough in the
Choosing an insulin regimen: a patient-centered approach
Abstract
Choosing the best insulin regimen for patients with type 1 diabetes mellitus (T1DM) requires the most personalized and thoughtful approach. It has been demonstrated that the continuous subcutaneous insulin infusion (CSII) using insulin pump has many advantages. Nevertheless,
Type 2 diabetes mellitus, non-alcoholic fatty liver disease and cardiovascular complications: what do they have in common?
Abstract
In clinical practice, doctors often meet with patients with non-alcoholic fatty liver disease in combination with type 2 diabetes mellitus and cardiovascular diseases. The mechanisms of their coexistence are not fully understood. Given that both diseases and their
Hypertriglyceridemia – a new and important present
Abstract
Current clinical recommendations for the treatment of dyslipidemia are aimed at reducing the concentration of low-density lipoprotein cholesterol (LDL cholesterol) to reduce the risk of atherosclerosis-associated cardiovascular diseases (AACD), however, clinical studies
Telomere biology and target-based approach in correction of insulin resistance in patients with prediabetes
Abstract
Changes in arterial wall properties due to carbohydrate metabolism disorders include an increase in their rigidity and an increase in wall thickness (primarily due to intimal thickening), appearance of subclinical atherosclerosis and endothelial dysfunction. It is possible
Liraglutide and sibutramine: similarities and differences in pharmacotherapy of obesity
Abstract
The centrally acting anti-obesity drugs currently registered in the Russian Federation include liraglutide 3.0 mg (Saxenda®, Enligria®) and a number of sibutramine-containing drugs, including Reduxin®, Reduxin Forte®. This literature review compares data
Thyroid disorders in polycystic ovary syndrome patients
Abstract
Polycystic ovary syndrome (PCOS) and hypothyroidism are some of the most common endocrinopathies seen in females. Thyroid disorders, especially Hashimoto’s thyroiditis (HT), and polycystic ovary syndrome (PCOS) are closely associated, based on a number of studies