Beta - cell mass and function are decreased to varying degrees in diabetes . Islet cell replacement or regenerative therapy may offer great therapeutic promise to people with diabetes. In addition to primary pancreatic p cells, recent studies on regeneration of functional

In this article such pathology as diabetes mellitus type 2 is described. Main types of therapy and mechanisms of drugs action are described. Last clinical trials data are represented. Also detailed information about glibenclamide prescription, action and advantages for

The paper discusses the features of the diabetes mellitus type 2 management when DPP-4 inhibitor linagliptin is included in the glucose-lowering therapy for the different clinical groups – the elderly patients and the patients with the renal and hepatic impairment and

80% of patients with diabetes mellitus are overweight or obese. One of medications focused on obesity management is sibutramine (Reduksin®). This article gives a detailed account of its mechanisms of action, side effects and data of foreign drug administration clinical

Glucose testing is universally utilized in the diagnosis and management of hyperglycemic and hypoglycemic disorders, and is probably the most common medical test. A great variety of glucose testing methods is currently available, and each method has its specific utility and

Main pathogenetic mechanisms of diabetes mellitus and its complications development are processes of freeradical oxidation. Substances with antioxidant activity of naturally occurring are actively studied as an additional metabolic support of diabetes mellitus. Among other

Introduction . Diabetes is a serious medical and social problem of all countries and of all ages. The combination of the diabetes mellitus type 2 and coronary heart disease according to some data is near 70–80% among patients with diabetes. The most significant risk

The aim of the research was the study of the awareness of the broad masses of the Moscow region population about the importance, clinical presentation and prevention of osteoporosis (OP) and fractures. Materials and methods: a questionnaire survey of a random sample of 2024

Objective – to evaluate the features of HRV (as a predictor of sudden increase in cardiovascular mortality from arrhythmia) due to hypoglycemia mild to moderate severity. Methods. It was conducted joint monitoring of blood glucose (CGMS) and Holter monitoring, 60

Objective – to evaluate the effect of sitagliptin in combination with metformin on glucose toxicity and lipotoxicity in patients with type 2 diabetes and obesity. Methods. The study involved 82 patients (55 women, 27 men, mean age 56,1±5,47 years) with obesity,

Introduction . Diabetes mellitus type 2 is a chronic, progressive disease that can lead to the development of microand macrovascular complications. An early sign of atherosclerosis is vascular endothelial damage, which develops over many years before the onset of

Patients with diabetes mellitus type 1 statistically make 12–15% of the total number of patients with diabetes. Generally they are young people who try to lead an active way of life and seek to be full-fledged members of society. While providing the hospital medical

Introduction . Increase in the incidence of diabetes mellitus (DM) and more rapid increase in the number of people with a condition called pre-diabetes, determine the need for a paradigm shift: the transition from diabetes diagnosis, treatment based on a physician if

Aim . To evaluate the effect of hyperglycemia, hypoglycemia and dysglycemia on the course and prognosis of acute myocardial infarction in patients with diabetes mellitus type 2. Methods. All patients admitted to the ICU with symptoms of acute myocardial infarction and

Thyroid cancer is the most common endocrine malignancy , accounting for 3% of all new malignant tumors diagnosed annually in the Russian Federation . Thyroid carcinoma metastasize in the cervical lymph nodes in 70% cases. Surgical method is the primary method of treatment of

Introduction: the relevance of combing diabetes mellitus type 2 (DM2) and the problem of androgenodeficiency (testosterone deficiency) in men depend on the high risk of developing cardiovascular complications. Cardiovascular diseases are the main cause of high mortality rate

Aim: improve management of diabetes mellitus type 2 by early intervention therapies aimed at correcting glucotoxicity and lipotoxicity. Methods. Patients with newly diagnosed diabetes mellitus type 2 evaluated the glycemic and lipid profile, free fatty acids, fatty acids