Эндокринология № 4 (41), 2022


News, Opinions, Training

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Topic number
4 . 2022

Congratulations on the 2022 Government of the Russian Federation award in the field of education


Modern aspects of type 2 diabetes mellitus pathogenesis: β-cell, what’s wrong with you?

As part of the IX National Diabetes Congress with international participation “Diabetes Mellitus and Obesity – the Non-Infectious Interdisciplinary Pandemics of the 21 st Century” on September 7, 2022, a plenary lecture was held by Honored Scientist of the
Original research

Anthropometric, metabolic parameters and cognitive functions investigation in patients with obesity treated with liraglutide 3 mg

Obesity is one of the most serious public health problems. Excess adipose tissue, especially visceral tissue, is associated with decreased cognitive function. In this connection, it is relevant to study the possibilities of modern groups of encreatin drugs for correction not

Diabetic sensorimotor polyneuropathy – a cholistic approach

Diabetic sensorimotor polyneuropathy (DSMPN) manifests as widespread but underdiagnosed complication of diabetes and prediabetes, lead to chronic pain and foot ulcer and and reduces quality of life. A summary review of internationally agreed expert recommendations is

Prognosis of long-term results of surgical and drug treatment of patients with acromegaly syndrome

This review discusses the problems of predicting long-term results of surgical and drug treatment of patients with acromegaly, taking into account multiple pathomorphological variants of somatotrophic adenomas. It was noted that rarely granular somatotrophic adenomas are

Cognitive impairment among patients with diabetes. Role of cobalamin

Diabetes mellitus is associated with an increased risk of cerebrovascular pathology and cognitive impairments. Genesis of cognitive impairments in patients with diabetes mellitus is complex. The leading role is given to cerebrovascular diseases. In addition, great importance

Fear of hypoglycemia: a new therapeutic target

Fear of hypoglycemia (FOH) is a factor that significantly limits glycemic control in patients with diabetes mellitus (DM) receiving insulin therapy. Pronounced FOH encourages patients to consume additional carbohydrates, maintain hyperglycemia, limit physical activity and

Pleiotropic effects of taurine in treatment of a patient with diabetes mellitus

The review presents data from experimental and clinical studies that indicate the possibility and ways of the effect of taurine on the level of glycemia, insulin resistance, dyslipidemia in patients with diabetes mellitus. Possible metabolic and molecular mechanisms of

Management of obesity: pharmacological approach

Today, weight gain has a number of negative consequences, including a significant increase in the risk of diabetes mellitus. This article highlights the evidence on the effects of drug therapy with sibutramine, a neurotransmitter reuptake inhibitor, and its effects in
Clinical cases

Use of Subetta® in the treatment of impaired glucose tolerance in a patient with metformin intolerance (clinical case)

The aim of the article is to show the possibility of Subetta® using in impaired glucose tolerance treatment based on a clinical case report. Material and methods. Prescription of Subetta® for the patient with prediabetes has a positive effect on insulin resistance

The combination of giant diffuse toxic goiter and Bekhterev’s disease: a clinical observation

A singularity of the presented clinical case is the presence of severe thyrotoxicosis in the patient with a long course of Graves disease together with a long history of ankylosing spondylitis. In addition, the patient has a large number of concomitant diseases. This

Timely diagnosis and correction of obstructive sleep apnea and sleep and wake rhythm disorders in the management of cardiometabolic health in patients with type 2 diabetes mellitus

Sleep disorders, including obstructive sleep apnea, are common in type 2 diabetes, but in most patients this problem is not given due attention due to the lack of information in the Russian clinical guidelines “Type 2 diabetes in adults” and, thus, low awareness

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Comparative characteristics of hypogonadotropic hypogonadism and constitutional delay of puberty in girls

The aim of this study was to evaluate of the role of clinical laboratory and genitometric indicators in the differential diagnosis of constitutional puberty delay and hypogonadotropic hypogonadism in girls. The results were obtained based on the examination of 23 patients

Comparative analysis of the ovarian reserve in women with different body mass index in reproductive age

The study is focused on the impact of overweight and obesity on the ovarian reserve. The study tested the relationship between anti-M ü llerian hormone levels and carbohydrate metabolism, as well as the evaluation of vitamin D level in women with different body mass

Bone remodeling in ovariectomized rats with experimental diabetes mellitus type 2 after canagliflozin treatment


We have done an experimental study of the effect of non-selective iSGLT‑2 canagliflozin on bone remodeling when it was used against the background of a combination of type 2 diabetes mellitus and menopause.

Causes of decompensation of diabetes mellitus in hospital patients

The aim of the study was to identify the causes of decompensation in patients with diabetes mellitus who are hospitalized. During the study, it was found that the most common causes of diabetes mellitus decompensation are: diet violation, physical activity disproportionate

Modern algorithm for topical diagnosis of endogenous hyperinsulinism


The study is devoted to a comparative analysis of methods for topical diagnosis of endogenous hyperinsulinism. Analysis of the obtained data demonstrated the possibility of reducing the diagnostic algorithm, as well as the importance of an integrated approach in diagnosis.

Clinical case of 24 years old woman with panhypopituitarism

A 24 year old woman was referred because of hypoglycemia. The woman had always been short and thin for her age. At the age of 15, she consulted a gynecologist for primary amenorrhea, but no diagnosis or treatment was prescribed for 5 years. It was only at the age of 20 that

The failure of the doctor–patient relationship model as a reason for low adherence to therapy

The problem of insufficient adherence to therapy has been posed for a long time, but remains very relevant to the present. Despite the versatility of the issue, often the blame for non-compliance with medical recommendations is placed on the patient. As part of the study, it

Clinical and laboratory characteristics of patients with type 2 diabetes hospitalized in foot rescue department

The aim of this study was to evaluate the clinical and laboratory characteristics of patients with type 2 diabetes mellitus hospitalized in foot rescue department. Results of the study showed that these patients have long experience of diabetes mellitus, uncontrolled

Comparative analysis of clinical and laboratory parameters of patients of the lower extremity rescue department depending on the presence or absence of diabetes mellitus

Diabetes mellitus is not only an independent chronic disease requiring serious treatment, but also an important risk factor for the development of many diseases based on atherosclerotic vascular lesion. In the course of a retrospective analysis of data from patients of the

Assessment of androgen status in men with type 2 diabetes mellitus

The clinical and laboratory parameters and the results of questionnaires of 45 men with type 2 diabetes mellitus (T2DM) aged 45–75 years with a duration of diabetes mellitus of 5–16 years were analyzed in order to determine the state of androgenic status, quality

Dill and parsley as a dietary supplement of vitamin K to food

Vitamin K – belongs to the group of fat-soluble vitamins. It occurs in two forms – in the form of phylloquinone (also known as vitamin K 1 ) and menaquinone (vitamin K 2 ). All vitamins K have menadion as a common ring structure, but differ from each other in the

Clinical and laboratory predictors of inefficiency of Helicobacter pylori eradication in patients with type 2 diabetes mellitus and chronic gastritis

The aim of the study is to predict the possible inefficiency of Helicobacter pylori eradication therapy in patients with type 2 diabetes mellitus using standard triple therapy enhanced with bismuth tripotassium dicitrate. The search was conducted by the ANOVA method.

The place of a multifactorial personalized approach in the diagnosis of thyroid nodules. Clinical case

This study assessed the results of fine needle aspiration biopsy (TAB) in patients with thyroid nodules in comparison with the diagnosis on admission and the postoperative diagnosis. In a number of patients there was a discrepancy between the above diagnoses and the TAB

Are diabetes mellitus and elevated body mass index risk factors for complicated course of the novel coronavirus infection?

The purpose of this study was to analyze the incidence of complications of a new coronavirus infection against the background of diabetes mellitus and various body mass index. Material and methods. The work was based on an assessment of the results of providing care to 403

Evaluation of the effectiveness of initial hypoglycemic therapy in patients with newly diagnosed type 2 diabetes mellitus using FreeStyle Libre

This study was aimed at evaluating the effectiveness of starting therapy in the monotherapy mode and various combinations of hypoglycemic drugs in patients with newly diagnosed type 2 diabetes mellitus using FreeStyle Libre flash monitoring. In the course of the work, it was
News of endocrinology

News (# 4, 2022)

Ametov Alexander S.
Honored Scientist of the Russian Federation, Doctor of Medical Sciences, Professor, Head of Subdepartment of Endocrinology, Head of the UNESCO Network Chair on the subject «Bioethics of diabetes as a global problem» of the Russian Medical Academy of Continuous Professional Education (Moscow)
Medicine today

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